A platform for glycoengineering a polyvalent pneumococcal bioconjugate vaccine using E. coli as a host.

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Title: A platform for glycoengineering a polyvalent pneumococcal bioconjugate vaccine using E. coli as a host.
Authors: Harding CM; VaxNewMo LLC, St. Louis, MO, 63108, USA. christian.harding@vaxnewmo.com., Nasr MA; Department of Biological Sciences, University of Alberta, Edmonton, AB, T6G 2R3, Canada.; Department of Biology, Centre for Applied Synthetic Biology, Concordia University, Montreal, QC, H4B 1R6, Canada., Scott NE; Department of Microbiology and Immunology, Institute for Infection and Immunity, University of Melbourne at the Peter Doherty, Parkville, VIC, 3010, Australia., Goyette-Desjardins G; Swine and Poultry Infectious Diseases Research Center, Faculty of Veterinary Medicine, University of Montreal, 3200 Sicotte Street, St-Hyacinthe, QC, J2S 2M2, Canada., Nothaft H; Department of Biological Sciences, University of Alberta, Edmonton, AB, T6G 2R3, Canada., Mayer AE; Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, 63110, USA., Chavez SM; Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, 63110, USA., Huynh JP; Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, 63110, USA., Kinsella RL; Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, 63110, USA., Szymanski CM; Department of Microbiology and Complex Carbohydrate Research Center, University of Georgia, Athens, GA, 30602, USA., Stallings CL; Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, 63110, USA., Segura M; Swine and Poultry Infectious Diseases Research Center, Faculty of Veterinary Medicine, University of Montreal, 3200 Sicotte Street, St-Hyacinthe, QC, J2S 2M2, Canada., Feldman MF; VaxNewMo LLC, St. Louis, MO, 63108, USA. mariofeldman@wustl.edu.; Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, 63110, USA. mariofeldman@wustl.edu.
Source: Nature communications [Nat Commun] 2019 Feb 21; Vol. 10 (1), pp. 891. Date of Electronic Publication: 2019 Feb 21.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-019-08869-9