Synthesis, structure-activity relationship and in vitro pharmacodynamics of A-ring modified caged xanthones in a preclinical model of inflammatory breast cancer.

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Title: Synthesis, structure-activity relationship and in vitro pharmacodynamics of A-ring modified caged xanthones in a preclinical model of inflammatory breast cancer.
Authors: Chantarasriwong O; Department of Chemistry and Biochemistry, University of California, 9500 Gilman Drive, La Jolla, San Diego, CA, 92093-0358, USA; Department of Chemistry, Faculty of Science, King Mongkut's University of Technology Thonburi, 126 Pracha Uthit Rd., Bang Mod, Thung Khru, Bangkok, 10140, Thailand., Milcarek AT; Department of Molecular and Cellular Biosciences, Rowan University, Glassboro, NJ, 08028, USA., Morales TH; Department of Biology, Arcadia University, Glenside, PA, 19038, USA., Settle AL; Department of Biology, Arcadia University, Glenside, PA, 19038, USA., Rezende CO Jr; Department of Chemistry and Biochemistry, University of California, 9500 Gilman Drive, La Jolla, San Diego, CA, 92093-0358, USA., Althufairi BD; Department of Chemistry and Biochemistry, University of California, 9500 Gilman Drive, La Jolla, San Diego, CA, 92093-0358, USA., Theodoraki MA; Department of Biology, Arcadia University, Glenside, PA, 19038, USA. Electronic address: theodorakim@arcadia.edu., Alpaugh ML; Department of Molecular and Cellular Biosciences, Rowan University, Glassboro, NJ, 08028, USA. Electronic address: alpaugh@rowan.edu., Theodorakis EA; Department of Chemistry and Biochemistry, University of California, 9500 Gilman Drive, La Jolla, San Diego, CA, 92093-0358, USA. Electronic address: etheodorakis@ucsd.edu.
Source: European journal of medicinal chemistry [Eur J Med Chem] 2019 Apr 15; Vol. 168, pp. 405-413. Date of Electronic Publication: 2019 Feb 20.
Publication Type: Journal Article
Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1768-3254
DOI:10.1016/j.ejmech.2019.02.047