Identification of Leishmania major UDP-Sugar Pyrophosphorylase Inhibitors Using Biosensor-Based Small Molecule Fragment Library Screening.

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Title: Identification of Leishmania major UDP-Sugar Pyrophosphorylase Inhibitors Using Biosensor-Based Small Molecule Fragment Library Screening.
Authors: Prakash O; Department of Clinical Biochemistry OE4340, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany. Prakash.Ohm@mh-hannover.de., Führing J; Department of Clinical Biochemistry OE4340, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany. Fuehring.Jana@mh-hannover.de., Post J; School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK. j.m.z.post@dundee.ac.uk., Shepherd SM; School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK. S.M.Shepherd@dundee.ac.uk., Eadsforth TC; School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK. t.eadsforth@dundee.ac.uk., Gray D; School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK. d.w.gray@dundee.ac.uk., Fedorov R; Institute for Biophysical Chemistry, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany. Fedorov.Roman@mh-hannover.de., Routier FH; Department of Clinical Biochemistry OE4340, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany. Routier.Francoise@mh-hannover.de.
Source: Molecules (Basel, Switzerland) [Molecules] 2019 Mar 12; Vol. 24 (5). Date of Electronic Publication: 2019 Mar 12.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1420-3049
DOI:10.3390/molecules24050996