Risk-modeling of dog osteosarcoma genome scans shows individuals with Mendelian-level polygenic risk are common.
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| Title: | Risk-modeling of dog osteosarcoma genome scans shows individuals with Mendelian-level polygenic risk are common. |
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| Authors: | Zapata I; Department of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, Columbus, OH, USA. zapata.11@buckeyemail.osu.edu., Moraes LE; Department of Animal Sciences, The Ohio State University College of Food, Agricultural and Environmental Sciences, Columbus, OH, USA., Fiala EM; Center for Molecular and Human Genetics, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.; Present address: Clinical Genetics Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Zaldivar-Lopez S; Department of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, Columbus, OH, USA.; Present address: Genomics and Animal Breeding Group, Department of Genetics, Faculty of Veterinary Medicine, University of Cordoba, 14071, Córdoba, Spain., Couto CG; Department of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, Columbus, OH, USA.; Couto Veterinary Consultants, Hilliard, OH, USA., Rowell JL; Center for Molecular and Human Genetics, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.; Department of Nursing, The Ohio State University College of Nursing, Columbus, OH, USA., Alvarez CE; Department of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, Columbus, OH, USA. carlos.alvarez@nationwidechildrens.org.; Center for Molecular and Human Genetics, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA. carlos.alvarez@nationwidechildrens.org.; Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, USA. carlos.alvarez@nationwidechildrens.org. |
| Source: | BMC genomics [BMC Genomics] 2019 Mar 19; Vol. 20 (1), pp. 226. Date of Electronic Publication: 2019 Mar 19. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164 (Electronic) Linking ISSN: 14712164 NLM ISO Abbreviation: BMC Genomics |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1471-2164 |
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| DOI: | 10.1186/s12864-019-5531-6 |
