Pharmacologic or genetic activation of SIRT1 attenuates the fat-induced decrease in beta-cell function in vivo.

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Title: Pharmacologic or genetic activation of SIRT1 attenuates the fat-induced decrease in beta-cell function in vivo.
Authors: Desai T; Department of Physiology, University of Toronto, Toronto, ON, Canada., Koulajian K; Department of Physiology, University of Toronto, Toronto, ON, Canada., Ivovic A; Department of Physiology, University of Toronto, Toronto, ON, Canada., Breen DM; Department of Physiology, University of Toronto, Toronto, ON, Canada., Luu L; Department of Physiology, University of Toronto, Toronto, ON, Canada., Tsiani EL; Faculty of Applied Health Sciences, Brock University, St. Catherines, ON, Canada., Wheeler MB; Department of Physiology, University of Toronto, Toronto, ON, Canada.; Department of Medicine, University of Toronto, Toronto, ON, Canada.; Banting and Best Diabetes Centre, University of Toronto, Toronto, ON, Canada., Giacca A; Department of Physiology, University of Toronto, Toronto, ON, Canada. adria.giacca@utoronto.ca.; Department of Medicine, University of Toronto, Toronto, ON, Canada. adria.giacca@utoronto.ca.; Banting and Best Diabetes Centre, University of Toronto, Toronto, ON, Canada. adria.giacca@utoronto.ca.; Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada. adria.giacca@utoronto.ca.
Source: Nutrition & diabetes [Nutr Diabetes] 2019 Mar 19; Vol. 9 (1), pp. 11. Date of Electronic Publication: 2019 Mar 19.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101566341 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-4052 (Electronic) Linking ISSN: 20444052 NLM ISO Abbreviation: Nutr Diabetes Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2044-4052
DOI:10.1038/s41387-019-0075-z