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Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.

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Title: Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
Authors: Baragaña B; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Forte B; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Choi R; Seattle Structural Genomics Center for Infectious Disease, Seattle, WA 98109.; Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA 98109.; Center for Emerging and Re-emerging Infectious Diseases, University of Washington, Seattle, WA 98109., Nakazawa Hewitt S; Seattle Structural Genomics Center for Infectious Disease, Seattle, WA 98109.; Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA 98109.; Center for Emerging and Re-emerging Infectious Diseases, University of Washington, Seattle, WA 98109., Bueren-Calabuig JA; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Pisco JP; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Peet C; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Dranow DM; Seattle Structural Genomics Center for Infectious Disease, Seattle, WA 98109.; Beryllium Discovery Corp., Bainbridge Island, WA 98110., Robinson DA; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Jansen C; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Norcross NR; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Vinayak S; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602., Anderson M; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Brooks CF; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602., Cooper CA; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602., Damerow S; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Delves M; Department of Life Sciences, Imperial College, South Kensington, SW7 2AZ London, United Kingdom., Dowers K; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Duffy J; Medicines for Malaria Venture, 1215 Geneva 15, Switzerland., Edwards TE; Seattle Structural Genomics Center for Infectious Disease, Seattle, WA 98109.; Beryllium Discovery Corp., Bainbridge Island, WA 98110., Hallyburton I; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Horst BG; Seattle Structural Genomics Center for Infectious Disease, Seattle, WA 98109.; Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA 98109.; Center for Emerging and Re-emerging Infectious Diseases, University of Washington, Seattle, WA 98109., Hulverson MA; Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA 98109.; Center for Emerging and Re-emerging Infectious Diseases, University of Washington, Seattle, WA 98109., Ferguson L; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Jiménez-Díaz MB; The Art of Discovery, 48160 Derio, Bizkaia, Basque Country, Spain., Jumani RS; Department of Medicine, University of Vermont, Burlington, VT 05405., Lorimer DD; Seattle Structural Genomics Center for Infectious Disease, Seattle, WA 98109.; Beryllium Discovery Corp., Bainbridge Island, WA 98110., Love MS; Biology Department, Calibr at Scripps Research, La Jolla, CA 92037., Maher S; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602., Matthews H; Department of Life Sciences, Imperial College, South Kensington, SW7 2AZ London, United Kingdom., McNamara CW; Biology Department, Calibr at Scripps Research, La Jolla, CA 92037., Miller P; Department of Medicine, University of Vermont, Burlington, VT 05405., O'Neill S; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Ojo KK; Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA 98109.; Center for Emerging and Re-emerging Infectious Diseases, University of Washington, Seattle, WA 98109., Osuna-Cabello M; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Pinto E; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Post J; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Riley J; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Rottmann M; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, CH-4002 Basel, Switzerland.; Universität Basel, CH-4003 Basel, Switzerland., Sanz LM; Diseases of the Developing World, Global Health, GlaxoSmithKline, 28760 Tres Cantos, Madrid, Spain., Scullion P; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Sharma A; Structural Parasitology Group, International Centre for Genetic Engineering and Biotechnology, 110067 New Delhi, India., Shepherd SM; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Shishikura Y; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Simeons FRC; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Stebbins EE; Department of Medicine, University of Vermont, Burlington, VT 05405., Stojanovski L; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Straschil U; Department of Life Sciences, Imperial College, South Kensington, SW7 2AZ London, United Kingdom., Tamaki FK; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Tamjar J; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Torrie LS; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Vantaux A; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 12 201 Phnom Penh, Cambodia., Witkowski B; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 12 201 Phnom Penh, Cambodia., Wittlin S; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, CH-4002 Basel, Switzerland.; Universität Basel, CH-4003 Basel, Switzerland., Yogavel M; Structural Parasitology Group, International Centre for Genetic Engineering and Biotechnology, 110067 New Delhi, India., Zuccotto F; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Angulo-Barturen I; The Art of Discovery, 48160 Derio, Bizkaia, Basque Country, Spain., Sinden R; Department of Life Sciences, Imperial College, South Kensington, SW7 2AZ London, United Kingdom., Baum J; Department of Life Sciences, Imperial College, South Kensington, SW7 2AZ London, United Kingdom., Gamo FJ; Diseases of the Developing World, Global Health, GlaxoSmithKline, 28760 Tres Cantos, Madrid, Spain., Mäser P; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, CH-4002 Basel, Switzerland.; Universität Basel, CH-4003 Basel, Switzerland., Kyle DE; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602., Winzeler EA; Skaggs School of Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093.; Department of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, CA 92093., Myler PJ; Seattle Structural Genomics Center for Infectious Disease, Seattle, WA 98109.; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109.; Department of Global Health, University of Washington, Seattle, WA 98195.; Department of Biomedical Informatics and Medical Education, University of Washington, Seattle, WA 98195., Wyatt PG; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Floyd D; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Matthews D; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Sharma A; Structural Parasitology Group, International Centre for Genetic Engineering and Biotechnology, 110067 New Delhi, India., Striepen B; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602.; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104., Huston CD; Department of Medicine, University of Vermont, Burlington, VT 05405., Gray DW; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Fairlamb AH; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Pisliakov AV; Computational Biology, School of Life Sciences, University of Dundee, DD1 5EH Dundee, United Kingdom.; Physics, School of Science and Engineering, University of Dundee, Dundee DD1 4HN, United Kingdom., Walpole C; Structural Genomics Consortium, Research Institute of the McGill University Health Centre, Montreal, QC H4A 3J1, Canada., Read KD; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom., Van Voorhis WC; Seattle Structural Genomics Center for Infectious Disease, Seattle, WA 98109.; Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA 98109.; Center for Emerging and Re-emerging Infectious Diseases, University of Washington, Seattle, WA 98109., Gilbert IH; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom; i.h.gilbert@dundee.ac.uk.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Apr 02; Vol. 116 (14), pp. 7015-7020. Date of Electronic Publication: 2019 Mar 20.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
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DbLabel: MEDLINE Ultimate
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PubType: Academic Journal
PubTypeId: academicJournal
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Items – Name: Title
  Label: Title
  Group: Ti
  Data: Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
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  Label: Authors
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  Data: <searchLink fieldCode="AU" term="%22Baragaña+B%22">Baragaña B</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Forte+B%22">Forte B</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Choi+R%22">Choi R</searchLink>; Seattle Structural Genomics Center for Infectious Disease, Seattle, WA 98109.; Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA 98109.; Center for Emerging and Re-emerging Infectious Diseases, University of Washington, Seattle, WA 98109.<br /><searchLink fieldCode="AU" term="%22Nakazawa+Hewitt+S%22">Nakazawa Hewitt S</searchLink>; Seattle Structural Genomics Center for Infectious Disease, Seattle, WA 98109.; Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA 98109.; Center for Emerging and Re-emerging Infectious Diseases, University of Washington, Seattle, WA 98109.<br /><searchLink fieldCode="AU" term="%22Bueren-Calabuig+JA%22">Bueren-Calabuig JA</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Pisco+JP%22">Pisco JP</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Peet+C%22">Peet C</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Dranow+DM%22">Dranow DM</searchLink>; Seattle Structural Genomics Center for Infectious Disease, Seattle, WA 98109.; Beryllium Discovery Corp., Bainbridge Island, WA 98110.<br /><searchLink fieldCode="AU" term="%22Robinson+DA%22">Robinson DA</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Jansen+C%22">Jansen C</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Norcross+NR%22">Norcross NR</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Vinayak+S%22">Vinayak S</searchLink>; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602.<br /><searchLink fieldCode="AU" term="%22Anderson+M%22">Anderson M</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Brooks+CF%22">Brooks CF</searchLink>; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602.<br /><searchLink fieldCode="AU" term="%22Cooper+CA%22">Cooper CA</searchLink>; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602.<br /><searchLink fieldCode="AU" term="%22Damerow+S%22">Damerow S</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Delves+M%22">Delves M</searchLink>; Department of Life Sciences, Imperial College, South Kensington, SW7 2AZ London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Dowers+K%22">Dowers K</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Duffy+J%22">Duffy J</searchLink>; Medicines for Malaria Venture, 1215 Geneva 15, Switzerland.<br /><searchLink fieldCode="AU" term="%22Edwards+TE%22">Edwards TE</searchLink>; Seattle Structural Genomics Center for Infectious Disease, Seattle, WA 98109.; Beryllium Discovery Corp., Bainbridge Island, WA 98110.<br /><searchLink fieldCode="AU" term="%22Hallyburton+I%22">Hallyburton I</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Horst+BG%22">Horst BG</searchLink>; Seattle Structural Genomics Center for Infectious Disease, Seattle, WA 98109.; Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA 98109.; Center for Emerging and Re-emerging Infectious Diseases, University of Washington, Seattle, WA 98109.<br /><searchLink fieldCode="AU" term="%22Hulverson+MA%22">Hulverson MA</searchLink>; Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA 98109.; Center for Emerging and Re-emerging Infectious Diseases, University of Washington, Seattle, WA 98109.<br /><searchLink fieldCode="AU" term="%22Ferguson+L%22">Ferguson L</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Jiménez-Díaz+MB%22">Jiménez-Díaz MB</searchLink>; The Art of Discovery, 48160 Derio, Bizkaia, Basque Country, Spain.<br /><searchLink fieldCode="AU" term="%22Jumani+RS%22">Jumani RS</searchLink>; Department of Medicine, University of Vermont, Burlington, VT 05405.<br /><searchLink fieldCode="AU" term="%22Lorimer+DD%22">Lorimer DD</searchLink>; Seattle Structural Genomics Center for Infectious Disease, Seattle, WA 98109.; Beryllium Discovery Corp., Bainbridge Island, WA 98110.<br /><searchLink fieldCode="AU" term="%22Love+MS%22">Love MS</searchLink>; Biology Department, Calibr at Scripps Research, La Jolla, CA 92037.<br /><searchLink fieldCode="AU" term="%22Maher+S%22">Maher S</searchLink>; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602.<br /><searchLink fieldCode="AU" term="%22Matthews+H%22">Matthews H</searchLink>; Department of Life Sciences, Imperial College, South Kensington, SW7 2AZ London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22McNamara+CW%22">McNamara CW</searchLink>; Biology Department, Calibr at Scripps Research, La Jolla, CA 92037.<br /><searchLink fieldCode="AU" term="%22Miller+P%22">Miller P</searchLink>; Department of Medicine, University of Vermont, Burlington, VT 05405.<br /><searchLink fieldCode="AU" term="%22O'Neill+S%22">O'Neill S</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Ojo+KK%22">Ojo KK</searchLink>; Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA 98109.; Center for Emerging and Re-emerging Infectious Diseases, University of Washington, Seattle, WA 98109.<br /><searchLink fieldCode="AU" term="%22Osuna-Cabello+M%22">Osuna-Cabello M</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Pinto+E%22">Pinto E</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Post+J%22">Post J</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Riley+J%22">Riley J</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Rottmann+M%22">Rottmann M</searchLink>; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, CH-4002 Basel, Switzerland.; Universität Basel, CH-4003 Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Sanz+LM%22">Sanz LM</searchLink>; Diseases of the Developing World, Global Health, GlaxoSmithKline, 28760 Tres Cantos, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Scullion+P%22">Scullion P</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Sharma+A%22">Sharma A</searchLink>; Structural Parasitology Group, International Centre for Genetic Engineering and Biotechnology, 110067 New Delhi, India.<br /><searchLink fieldCode="AU" term="%22Shepherd+SM%22">Shepherd SM</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Shishikura+Y%22">Shishikura Y</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Simeons+FRC%22">Simeons FRC</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Stebbins+EE%22">Stebbins EE</searchLink>; Department of Medicine, University of Vermont, Burlington, VT 05405.<br /><searchLink fieldCode="AU" term="%22Stojanovski+L%22">Stojanovski L</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Straschil+U%22">Straschil U</searchLink>; Department of Life Sciences, Imperial College, South Kensington, SW7 2AZ London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Tamaki+FK%22">Tamaki FK</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Tamjar+J%22">Tamjar J</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Torrie+LS%22">Torrie LS</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Vantaux+A%22">Vantaux A</searchLink>; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 12 201 Phnom Penh, Cambodia.<br /><searchLink fieldCode="AU" term="%22Witkowski+B%22">Witkowski B</searchLink>; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 12 201 Phnom Penh, Cambodia.<br /><searchLink fieldCode="AU" term="%22Wittlin+S%22">Wittlin S</searchLink>; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, CH-4002 Basel, Switzerland.; Universität Basel, CH-4003 Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Yogavel+M%22">Yogavel M</searchLink>; Structural Parasitology Group, International Centre for Genetic Engineering and Biotechnology, 110067 New Delhi, India.<br /><searchLink fieldCode="AU" term="%22Zuccotto+F%22">Zuccotto F</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Angulo-Barturen+I%22">Angulo-Barturen I</searchLink>; The Art of Discovery, 48160 Derio, Bizkaia, Basque Country, Spain.<br /><searchLink fieldCode="AU" term="%22Sinden+R%22">Sinden R</searchLink>; Department of Life Sciences, Imperial College, South Kensington, SW7 2AZ London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Baum+J%22">Baum J</searchLink>; Department of Life Sciences, Imperial College, South Kensington, SW7 2AZ London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gamo+FJ%22">Gamo FJ</searchLink>; Diseases of the Developing World, Global Health, GlaxoSmithKline, 28760 Tres Cantos, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Mäser+P%22">Mäser P</searchLink>; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, CH-4002 Basel, Switzerland.; Universität Basel, CH-4003 Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kyle+DE%22">Kyle DE</searchLink>; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602.<br /><searchLink fieldCode="AU" term="%22Winzeler+EA%22">Winzeler EA</searchLink>; Skaggs School of Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093.; Department of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, CA 92093.<br /><searchLink fieldCode="AU" term="%22Myler+PJ%22">Myler PJ</searchLink>; Seattle Structural Genomics Center for Infectious Disease, Seattle, WA 98109.; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109.; Department of Global Health, University of Washington, Seattle, WA 98195.; Department of Biomedical Informatics and Medical Education, University of Washington, Seattle, WA 98195.<br /><searchLink fieldCode="AU" term="%22Wyatt+PG%22">Wyatt PG</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Floyd+D%22">Floyd D</searchLink>; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada.<br /><searchLink fieldCode="AU" term="%22Matthews+D%22">Matthews D</searchLink>; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada.<br /><searchLink fieldCode="AU" term="%22Sharma+A%22">Sharma A</searchLink>; Structural Parasitology Group, International Centre for Genetic Engineering and Biotechnology, 110067 New Delhi, India.<br /><searchLink fieldCode="AU" term="%22Striepen+B%22">Striepen B</searchLink>; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602.; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104.<br /><searchLink fieldCode="AU" term="%22Huston+CD%22">Huston CD</searchLink>; Department of Medicine, University of Vermont, Burlington, VT 05405.<br /><searchLink fieldCode="AU" term="%22Gray+DW%22">Gray DW</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Fairlamb+AH%22">Fairlamb AH</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Pisliakov+AV%22">Pisliakov AV</searchLink>; Computational Biology, School of Life Sciences, University of Dundee, DD1 5EH Dundee, United Kingdom.; Physics, School of Science and Engineering, University of Dundee, Dundee DD1 4HN, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Walpole+C%22">Walpole C</searchLink>; Structural Genomics Consortium, Research Institute of the McGill University Health Centre, Montreal, QC H4A 3J1, Canada.<br /><searchLink fieldCode="AU" term="%22Read+KD%22">Read KD</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Van+Voorhis+WC%22">Van Voorhis WC</searchLink>; Seattle Structural Genomics Center for Infectious Disease, Seattle, WA 98109.; Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA 98109.; Center for Emerging and Re-emerging Infectious Diseases, University of Washington, Seattle, WA 98109.<br /><searchLink fieldCode="AU" term="%22Gilbert+IH%22">Gilbert IH</searchLink>; Wellcome Centre for Anti-Infectives Research, Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, DD1 5EH Dundee, United Kingdom; i.h.gilbert@dundee.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2019 Apr 02; Vol. 116 (14), pp. 7015-7020. <i>Date of Electronic Publication: </i>2019 Mar 20.
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  Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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              Text: 2019 Apr 02
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