LRRK2 modifies α-syn pathology and spread in mouse models and human neurons.

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Title: LRRK2 modifies α-syn pathology and spread in mouse models and human neurons.
Authors: Bieri G; Department of Genetics, Stanford University School of Medicine, 300 Pasteur Drive, M322 Alway Building, Stanford, CA, 94305-5120, USA.; Stanford Neurosciences Graduate Program, Stanford University School of Medicine, Stanford, CA, USA., Brahic M; Department of Genetics, Stanford University School of Medicine, 300 Pasteur Drive, M322 Alway Building, Stanford, CA, 94305-5120, USA., Bousset L; Institut François Jacob, MIRCen, CEA and Laboratory of Neurodegenerative Diseases, CNRS, Fontenay-aux-Roses, France., Couthouis J; Department of Genetics, Stanford University School of Medicine, 300 Pasteur Drive, M322 Alway Building, Stanford, CA, 94305-5120, USA., Kramer NJ; Department of Genetics, Stanford University School of Medicine, 300 Pasteur Drive, M322 Alway Building, Stanford, CA, 94305-5120, USA.; Stanford Neurosciences Graduate Program, Stanford University School of Medicine, Stanford, CA, USA., Ma R; Department of Genetics, Stanford University School of Medicine, 300 Pasteur Drive, M322 Alway Building, Stanford, CA, 94305-5120, USA., Nakayama L; Department of Genetics, Stanford University School of Medicine, 300 Pasteur Drive, M322 Alway Building, Stanford, CA, 94305-5120, USA., Monbureau M; Stanford Behavioral and Functional Neuroscience Laboratory, Stanford University, Stanford, CA, USA.; Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA., Defensor E; Stanford Behavioral and Functional Neuroscience Laboratory, Stanford University, Stanford, CA, USA.; Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA., Schüle B; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Shamloo M; Stanford Behavioral and Functional Neuroscience Laboratory, Stanford University, Stanford, CA, USA.; Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA., Melki R; Institut François Jacob, MIRCen, CEA and Laboratory of Neurodegenerative Diseases, CNRS, Fontenay-aux-Roses, France., Gitler AD; Department of Genetics, Stanford University School of Medicine, 300 Pasteur Drive, M322 Alway Building, Stanford, CA, 94305-5120, USA. agitler@stanford.edu.; Stanford Neurosciences Graduate Program, Stanford University School of Medicine, Stanford, CA, USA. agitler@stanford.edu.
Source: Acta neuropathologica [Acta Neuropathol] 2019 Jun; Vol. 137 (6), pp. 961-980. Date of Electronic Publication: 2019 Mar 29.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1432-0533
DOI:10.1007/s00401-019-01995-0