The phytochemical polydatin ameliorates non-alcoholic steatohepatitis by restoring lysosomal function and autophagic flux.

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Title: The phytochemical polydatin ameliorates non-alcoholic steatohepatitis by restoring lysosomal function and autophagic flux.
Authors: Chen X; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, People's Republic of China.; Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China., Chan H; Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Shatin, Hong Kong., Zhang L; Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Shatin, Hong Kong.; State Key Laboratory of Digestive Diseases, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong.; CUHK Shenzhen Research Institute, Shenzhen, People's Republic of China., Liu X; Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Shatin, Hong Kong., Ho IHT; Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Shatin, Hong Kong., Zhang X; State Key Laboratory of Digestive Diseases, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong.; Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong., Ho J; Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Shatin, Hong Kong., Hu W; Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Shatin, Hong Kong., Tian Y; Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Shatin, Hong Kong., Kou S; Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Shatin, Hong Kong., Chan CS; Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Shatin, Hong Kong., Yu J; State Key Laboratory of Digestive Diseases, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong.; CUHK Shenzhen Research Institute, Shenzhen, People's Republic of China.; Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong., Wong SH; State Key Laboratory of Digestive Diseases, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong.; CUHK Shenzhen Research Institute, Shenzhen, People's Republic of China.; Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong., Gin T; Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Shatin, Hong Kong., Chan MTV; Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Shatin, Hong Kong., Sun X; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, People's Republic of China., Wu WKK; Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Shatin, Hong Kong.; State Key Laboratory of Digestive Diseases, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong.; CUHK Shenzhen Research Institute, Shenzhen, People's Republic of China.
Source: Journal of cellular and molecular medicine [J Cell Mol Med] 2019 Jun; Vol. 23 (6), pp. 4290-4300. Date of Electronic Publication: 2019 Apr 11.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101083777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1582-4934 (Electronic) Linking ISSN: 15821838 NLM ISO Abbreviation: J Cell Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1582-4934
DOI:10.1111/jcmm.14320