Slow-release delivery enhances the pharmacological properties of oral 5-hydroxytryptophan: mouse proof-of-concept.

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Title: Slow-release delivery enhances the pharmacological properties of oral 5-hydroxytryptophan: mouse proof-of-concept.
Authors: Jacobsen JPR; Department of Cell Biology, Duke University, Durham, NC, 27710, USA., Oh A; Department of Cell Biology, Duke University, Durham, NC, 27710, USA., Bangle R; Department of Cell Biology, Duke University, Durham, NC, 27710, USA., Roberts WL; Department of Cell Biology, Duke University, Durham, NC, 27710, USA., Royer EL; Department of Cell Biology, Duke University, Durham, NC, 27710, USA., Modesto N; Department of Cell Biology, Duke University, Durham, NC, 27710, USA., Windermere SA; Department of Cell Biology, Duke University, Durham, NC, 27710, USA., Yi Z; Department of Cell Biology, Duke University, Durham, NC, 27710, USA., Vernon R; Department of Cell Biology, Duke University, Durham, NC, 27710, USA., Cajina M; Lundbeck Research USA, Paramus, NJ, 07652, USA., Urs NM; Department of Pharmacology and Therapeutics, University of Florida, 1200 Newell Dr, Gainesville, FL, 32610, USA., Snyder JC; Department of Cell Biology, Duke University, Durham, NC, 27710, USA., Nicholls PJ; Department of Cell Biology, Duke University, Durham, NC, 27710, USA., Sachs BD; Department of Psychology, Villanova University College of Liberal Arts and Sciences, Villanova, PA, 19085, USA., Caron MG; Department of Cell Biology, Duke University, Durham, NC, 27710, USA. marc.caron@duke.edu.; Department of Medicine, Duke University, Durham, NC, 27710, USA. marc.caron@duke.edu.; Department of Neurobiology, Duke University, Durham, NC, 27710, USA. marc.caron@duke.edu.
Source: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology [Neuropsychopharmacology] 2019 Nov; Vol. 44 (12), pp. 2082-2090. Date of Electronic Publication: 2019 Apr 29.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8904907 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1740-634X (Electronic) Linking ISSN: 0893133X NLM ISO Abbreviation: Neuropsychopharmacology Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1740-634X
DOI:10.1038/s41386-019-0400-1