Liver safety evaluation of endothelin receptor antagonists using HepatoPac® : A single model impact assessment on hepatocellular health, function and bile acid disposition.
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| Title: | Liver safety evaluation of endothelin receptor antagonists using HepatoPac® : A single model impact assessment on hepatocellular health, function and bile acid disposition. |
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| Authors: | Aleo MD; Drug Safety Research and Development, Worldwide Research & Development, Pfizer Inc., Groton, Connecticut., Ukairo O; BioIVT, formerly Hepregen Corporation, Medford, Massachusetts., Moore A; BioIVT, formerly Hepregen Corporation, Medford, Massachusetts., Irrechukwu O; BioIVT, formerly Hepregen Corporation, Medford, Massachusetts., Potter DM; Drug Safety Research and Development, Worldwide Research & Development, Pfizer Inc., Groton, Connecticut., Schneider RP; Pharmacokinetics, Dynamics and Metabolism, Worldwide Research & Development, Pfizer Inc., Groton, Connecticut. |
| Source: | Journal of applied toxicology : JAT [J Appl Toxicol] 2019 Aug; Vol. 39 (8), pp. 1192-1207. Date of Electronic Publication: 2019 May 27. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: John Wiley And Sons Country of Publication: England NLM ID: 8109495 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1099-1263 (Electronic) Linking ISSN: 0260437X NLM ISO Abbreviation: J Appl Toxicol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1099-1263 |
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| DOI: | 10.1002/jat.3805 |
