A T164S mutation in the dengue virus NS1 protein is associated with greater disease severity in mice.
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| Title: | A T164S mutation in the dengue virus NS1 protein is associated with greater disease severity in mice. |
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| Authors: | Chan KWK; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.; Department of Microbiology and Immunology, 5 Science Drive 2, Singapore 117545, Singapore., Watanabe S; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore., Jin JY; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore., Pompon J; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.; MIVEGEC, UMR IRD 224-CNRS5290 Université de Montpellier, Montpellier, France., Teng D; Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia., Alonso S; Department of Microbiology and Immunology, 5 Science Drive 2, Singapore 117545, Singapore.; Immunology Programme, Life Science Institute, National University of Singapore, Singapore 117456, Singapore., Vijaykrishna D; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.; Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia., Halstead SB; Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, MD 20817, USA., Marzinek JK; Bioinformatics Institute (A*STAR), 30 Biopolis St., Singapore 138671, Singapore., Bond PJ; Bioinformatics Institute (A*STAR), 30 Biopolis St., Singapore 138671, Singapore., Burla B; Singapore Lipidomics Incubator (SLING), Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore., Torta F; Singapore Lipidomics Incubator (SLING), Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore., Wenk MR; Singapore Lipidomics Incubator (SLING), Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore., Ooi EE; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.; Department of Microbiology and Immunology, 5 Science Drive 2, Singapore 117545, Singapore., Vasudevan SG; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore. subhash.vasudevan@duke-nus.edu.sg.; Department of Microbiology and Immunology, 5 Science Drive 2, Singapore 117545, Singapore. |
| Source: | Science translational medicine [Sci Transl Med] 2019 Jun 26; Vol. 11 (498). |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1946-6242 |
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| DOI: | 10.1126/scitranslmed.aat7726 |
