A T164S mutation in the dengue virus NS1 protein is associated with greater disease severity in mice.

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Title: A T164S mutation in the dengue virus NS1 protein is associated with greater disease severity in mice.
Authors: Chan KWK; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.; Department of Microbiology and Immunology, 5 Science Drive 2, Singapore 117545, Singapore., Watanabe S; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore., Jin JY; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore., Pompon J; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.; MIVEGEC, UMR IRD 224-CNRS5290 Université de Montpellier, Montpellier, France., Teng D; Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia., Alonso S; Department of Microbiology and Immunology, 5 Science Drive 2, Singapore 117545, Singapore.; Immunology Programme, Life Science Institute, National University of Singapore, Singapore 117456, Singapore., Vijaykrishna D; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.; Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia., Halstead SB; Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, MD 20817, USA., Marzinek JK; Bioinformatics Institute (A*STAR), 30 Biopolis St., Singapore 138671, Singapore., Bond PJ; Bioinformatics Institute (A*STAR), 30 Biopolis St., Singapore 138671, Singapore., Burla B; Singapore Lipidomics Incubator (SLING), Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore., Torta F; Singapore Lipidomics Incubator (SLING), Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore., Wenk MR; Singapore Lipidomics Incubator (SLING), Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore., Ooi EE; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.; Department of Microbiology and Immunology, 5 Science Drive 2, Singapore 117545, Singapore., Vasudevan SG; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore. subhash.vasudevan@duke-nus.edu.sg.; Department of Microbiology and Immunology, 5 Science Drive 2, Singapore 117545, Singapore.
Source: Science translational medicine [Sci Transl Med] 2019 Jun 26; Vol. 11 (498).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
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  Data: A T164S mutation in the dengue virus NS1 protein is associated with greater disease severity in mice.
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  Data: <searchLink fieldCode="AU" term="%22Chan+KWK%22">Chan KWK</searchLink>; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.; Department of Microbiology and Immunology, 5 Science Drive 2, Singapore 117545, Singapore.<br /><searchLink fieldCode="AU" term="%22Watanabe+S%22">Watanabe S</searchLink>; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.<br /><searchLink fieldCode="AU" term="%22Jin+JY%22">Jin JY</searchLink>; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.<br /><searchLink fieldCode="AU" term="%22Pompon+J%22">Pompon J</searchLink>; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.; MIVEGEC, UMR IRD 224-CNRS5290 Université de Montpellier, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Teng+D%22">Teng D</searchLink>; Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia.<br /><searchLink fieldCode="AU" term="%22Alonso+S%22">Alonso S</searchLink>; Department of Microbiology and Immunology, 5 Science Drive 2, Singapore 117545, Singapore.; Immunology Programme, Life Science Institute, National University of Singapore, Singapore 117456, Singapore.<br /><searchLink fieldCode="AU" term="%22Vijaykrishna+D%22">Vijaykrishna D</searchLink>; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.; Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia.<br /><searchLink fieldCode="AU" term="%22Halstead+SB%22">Halstead SB</searchLink>; Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, MD 20817, USA.<br /><searchLink fieldCode="AU" term="%22Marzinek+JK%22">Marzinek JK</searchLink>; Bioinformatics Institute (A*STAR), 30 Biopolis St., Singapore 138671, Singapore.<br /><searchLink fieldCode="AU" term="%22Bond+PJ%22">Bond PJ</searchLink>; Bioinformatics Institute (A*STAR), 30 Biopolis St., Singapore 138671, Singapore.<br /><searchLink fieldCode="AU" term="%22Burla+B%22">Burla B</searchLink>; Singapore Lipidomics Incubator (SLING), Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.<br /><searchLink fieldCode="AU" term="%22Torta+F%22">Torta F</searchLink>; Singapore Lipidomics Incubator (SLING), Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.<br /><searchLink fieldCode="AU" term="%22Wenk+MR%22">Wenk MR</searchLink>; Singapore Lipidomics Incubator (SLING), Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.<br /><searchLink fieldCode="AU" term="%22Ooi+EE%22">Ooi EE</searchLink>; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.; Department of Microbiology and Immunology, 5 Science Drive 2, Singapore 117545, Singapore.<br /><searchLink fieldCode="AU" term="%22Vasudevan+SG%22">Vasudevan SG</searchLink>; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore. subhash.vasudevan@duke-nus.edu.sg.; Department of Microbiology and Immunology, 5 Science Drive 2, Singapore 117545, Singapore.
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  Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2019 Jun 26; Vol. 11 (498).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+the+Advancement+of+Science%22">American Association for the Advancement of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101505086 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1946-6242 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219466234%22">19466234 </searchLink><i>NLM ISO Abbreviation: </i>Sci Transl Med <i>Subsets: </i>MEDLINE
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        Value: 10.1126/scitranslmed.aat7726
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      – TitleFull: A T164S mutation in the dengue virus NS1 protein is associated with greater disease severity in mice.
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              Text: 2019 Jun 26
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