A therapy with miglustat, 2-hydroxypropyl-ß-cyclodextrin and allopregnanolone restores splenic cholesterol homeostasis in Niemann-pick disease type C1.
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| Title: | A therapy with miglustat, 2-hydroxypropyl-ß-cyclodextrin and allopregnanolone restores splenic cholesterol homeostasis in Niemann-pick disease type C1. |
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| Authors: | Neßlauer AM; Institute of Anatomy, Rostock University Medical Center, Gertrudenstraße 9, 18057, Rostock, Germany., Gläser A; Institute of Anatomy, Rostock University Medical Center, Gertrudenstraße 9, 18057, Rostock, Germany.; Research Group Anatomy, School of Medicine and Health Sciences, Department für Humanmedizin, Abteilung Anatomie, Carl von Ossietzky University Oldenburg, Carl-von-Ossietzky Straße 9-11, 26129, Oldenburg, Germany., Gräler M; Department of Anesthesiology and Intensive Care Medicine, Center for Sepsis Control and Care (CSCC), and the Center for Molecular Biomedicine (CMB), Jena University Hospital, Hans-Knöll-Str. 2, 07745, Jena, Germany., Engelmann R; Institute of Immunology, Rostock University Medical Center, Schillingallee 70, 18057, Rostock, Germany., Müller-Hilke B; Institute of Immunology, Rostock University Medical Center, Schillingallee 70, 18057, Rostock, Germany., Frank M; Medical Biology and Electron Microscopy Center, Rostock University Medical Center, Strempelstraße 14, 18057, Rostock, Germany., Burstein C; Institute of Clinical Chemistry and Pathobiochemistry, Rostock University Medical Center, Ernst-Heydemann-Straße 6, 18057, Rostock, Germany., Rolfs A; Centogene AG, Am Strande 7, 18055, Rostock, Germany., Neidhardt J; Human Genetics, Faculty of Medicine and Health Sciences, University of Oldenburg, Oldenburg, Germany.; Research Center for Neurosensory Science, Carl von Ossietzky University Oldenburg, Oldenburg, Germany., Wree A; Institute of Anatomy, Rostock University Medical Center, Gertrudenstraße 9, 18057, Rostock, Germany., Witt M; Institute of Anatomy, Rostock University Medical Center, Gertrudenstraße 9, 18057, Rostock, Germany., Bräuer AU; Institute of Anatomy, Rostock University Medical Center, Gertrudenstraße 9, 18057, Rostock, Germany. anja.braeuer@uni-oldenburg.de.; Research Group Anatomy, School of Medicine and Health Sciences, Department für Humanmedizin, Abteilung Anatomie, Carl von Ossietzky University Oldenburg, Carl-von-Ossietzky Straße 9-11, 26129, Oldenburg, Germany. anja.braeuer@uni-oldenburg.de.; Research Center for Neurosensory Science, Carl von Ossietzky University Oldenburg, Oldenburg, Germany. anja.braeuer@uni-oldenburg.de. |
| Source: | Lipids in health and disease [Lipids Health Dis] 2019 Jun 28; Vol. 18 (1), pp. 146. Date of Electronic Publication: 2019 Jun 28. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101147696 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-511X (Electronic) Linking ISSN: 1476511X NLM ISO Abbreviation: Lipids Health Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1476-511X |
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| DOI: | 10.1186/s12944-019-1088-2 |
