Investigation of the role of typhoid toxin in acute typhoid fever in a human challenge model.
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| Title: | Investigation of the role of typhoid toxin in acute typhoid fever in a human challenge model. |
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| Authors: | Gibani MM; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK. malick.gibani@paediatrics.ox.ac.uk.; Department of Medicine, Imperial College London, London, UK. malick.gibani@paediatrics.ox.ac.uk., Jones E; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK., Barton A; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK., Jin C; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK., Meek J; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK., Camara S; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK., Galal U; Nuffield Department of Primary Care Health Sciences, Clinical Trials Unit, University of Oxford, Oxford, UK., Heinz E; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, UK., Rosenberg-Hasson Y; Human Immune Monitoring Center, Institute for Immunity, Transplantation and Infection, Stanford University, Stanford, CA, USA., Obermoser G; Human Immune Monitoring Center, Institute for Immunity, Transplantation and Infection, Stanford University, Stanford, CA, USA., Jones C; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK., Campbell D; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK., Black C; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK., Thomaides-Brears H; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK., Darlow C; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK., Dold C; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK., Silva-Reyes L; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK., Blackwell L; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK., Lara-Tejero M; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA., Jiao X; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA., Stack G; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA., Blohmke CJ; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK., Hill J; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK., Angus B; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Dougan G; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Department of Medicine, University of Cambridge, Hinxton, UK., Galán J; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA., Pollard AJ; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK. |
| Source: | Nature medicine [Nat Med] 2019 Jul; Vol. 25 (7), pp. 1082-1088. Date of Electronic Publication: 2019 Jul 03. |
| Publication Type: | Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 31270506 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Investigation of the role of typhoid toxin in acute typhoid fever in a human challenge model. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Gibani+MM%22">Gibani MM</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK. malick.gibani@paediatrics.ox.ac.uk.; Department of Medicine, Imperial College London, London, UK. malick.gibani@paediatrics.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Jones+E%22">Jones E</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Barton+A%22">Barton A</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Jin+C%22">Jin C</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Meek+J%22">Meek J</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Camara+S%22">Camara S</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Galal+U%22">Galal U</searchLink>; Nuffield Department of Primary Care Health Sciences, Clinical Trials Unit, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Heinz+E%22">Heinz E</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Rosenberg-Hasson+Y%22">Rosenberg-Hasson Y</searchLink>; Human Immune Monitoring Center, Institute for Immunity, Transplantation and Infection, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Obermoser+G%22">Obermoser G</searchLink>; Human Immune Monitoring Center, Institute for Immunity, Transplantation and Infection, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Jones+C%22">Jones C</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Campbell+D%22">Campbell D</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Black+C%22">Black C</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Thomaides-Brears+H%22">Thomaides-Brears H</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Darlow+C%22">Darlow C</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Dold+C%22">Dold C</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Silva-Reyes+L%22">Silva-Reyes L</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Blackwell+L%22">Blackwell L</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Lara-Tejero+M%22">Lara-Tejero M</searchLink>; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Jiao+X%22">Jiao X</searchLink>; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Stack+G%22">Stack G</searchLink>; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Blohmke+CJ%22">Blohmke CJ</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Hill+J%22">Hill J</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Angus+B%22">Angus B</searchLink>; Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Dougan+G%22">Dougan G</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Department of Medicine, University of Cambridge, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Galán+J%22">Galán J</searchLink>; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Pollard+AJ%22">Pollard AJ</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229502015%22">Nature medicine</searchLink> [Nat Med] 2019 Jul; Vol. 25 (7), pp. 1082-1088. <i>Date of Electronic Publication: </i>2019 Jul 03. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Company%22">Nature Publishing Company </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9502015 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1546-170X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210788956%22">10788956 </searchLink><i>NLM ISO Abbreviation: </i>Nat Med <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=31270506 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41591-019-0505-4 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1082 Titles: – TitleFull: Investigation of the role of typhoid toxin in acute typhoid fever in a human challenge model. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Gibani MM – PersonEntity: Name: NameFull: Jones E – PersonEntity: Name: NameFull: Barton A – PersonEntity: Name: NameFull: Jin C – PersonEntity: Name: NameFull: Meek J – PersonEntity: Name: NameFull: Camara S – PersonEntity: Name: NameFull: Galal U – PersonEntity: Name: NameFull: Heinz E – PersonEntity: Name: NameFull: Rosenberg-Hasson Y – PersonEntity: Name: NameFull: Obermoser G – PersonEntity: Name: NameFull: Jones C – PersonEntity: Name: NameFull: Campbell D – PersonEntity: Name: NameFull: Black C – PersonEntity: Name: NameFull: Thomaides-Brears H – PersonEntity: Name: NameFull: Darlow C – PersonEntity: Name: NameFull: Dold C – PersonEntity: Name: NameFull: Silva-Reyes L – PersonEntity: Name: NameFull: Blackwell L – PersonEntity: Name: NameFull: Lara-Tejero M – PersonEntity: Name: NameFull: Jiao X – PersonEntity: Name: NameFull: Stack G – PersonEntity: Name: NameFull: Blohmke CJ – PersonEntity: Name: NameFull: Hill J – PersonEntity: Name: NameFull: Angus B – PersonEntity: Name: NameFull: Dougan G – PersonEntity: Name: NameFull: Galán J – PersonEntity: Name: NameFull: Pollard AJ IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 07 Text: 2019 Jul Type: published Y: 2019 Identifiers: – Type: issn-electronic Value: 1546-170X Numbering: – Type: volume Value: 25 – Type: issue Value: 7 Titles: – TitleFull: Nature medicine Type: main |
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