A glycine-specific N-degron pathway mediates the quality control of protein N-myristoylation.

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Title: A glycine-specific N-degron pathway mediates the quality control of protein N-myristoylation.
Authors: Timms RT; Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA.; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Zhang Z; Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA.; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Rhee DY; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA., Harper JW; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA., Koren I; Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA. itay.koren@biu.ac.il selledge@genetics.med.harvard.edu.; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Elledge SJ; Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA. itay.koren@biu.ac.il selledge@genetics.med.harvard.edu.; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Source: Science (New York, N.Y.) [Science] 2019 Jul 05; Vol. 365 (6448).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1095-9203
DOI:10.1126/science.aaw4912