Indenoisoquinoline Topoisomerase Inhibitors Strongly Bind and Stabilize the MYC Promoter G-Quadruplex and Downregulate MYC.
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| Title: | Indenoisoquinoline Topoisomerase Inhibitors Strongly Bind and Stabilize the MYC Promoter G-Quadruplex and Downregulate MYC. |
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| Authors: | Wang KB; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy , Purdue University , 575 W Stadium Avenue , West Lafayette , Indiana 47907 , United States., Elsayed MSA; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy , Purdue University , 575 W Stadium Avenue , West Lafayette , Indiana 47907 , United States., Wu G; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy , Purdue University , 575 W Stadium Avenue , West Lafayette , Indiana 47907 , United States., Deng N; Department of Chemistry and Physical Sciences , Pace University , 1 Pace Plaza , New York , New York 10038 , United States., Cushman M; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy , Purdue University , 575 W Stadium Avenue , West Lafayette , Indiana 47907 , United States.; Purdue Center for Cancer Research , 201 S University Street , West Lafayette , Indiana 47906 , United States.; Purdue Institute for Drug Discovery , 720 Clinic Drive , West Lafayette , Indiana 47907 , United States., Yang D; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy , Purdue University , 575 W Stadium Avenue , West Lafayette , Indiana 47907 , United States.; Purdue Center for Cancer Research , 201 S University Street , West Lafayette , Indiana 47906 , United States.; Purdue Institute for Drug Discovery , 720 Clinic Drive , West Lafayette , Indiana 47907 , United States. |
| Source: | Journal of the American Chemical Society [J Am Chem Soc] 2019 Jul 17; Vol. 141 (28), pp. 11059-11070. Date of Electronic Publication: 2019 Jul 08. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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