Activation loop dynamics are controlled by conformation-selective inhibitors of ERK2.

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Bibliographic Details
Title: Activation loop dynamics are controlled by conformation-selective inhibitors of ERK2.
Authors: Pegram LM; Department of Biochemistry, University of Colorado, Boulder, CO 80305., Liddle JC; Department of Biochemistry, University of Colorado, Boulder, CO 80305., Xiao Y; Department of Biochemistry, University of Colorado, Boulder, CO 80305., Hoh M; Department of Biochemistry, University of Colorado, Boulder, CO 80305., Rudolph J; Department of Biochemistry, University of Colorado, Boulder, CO 80305., Iverson DB; Department of Biochemistry, University of Colorado, Boulder, CO 80305., Vigers GP; Structural Biology Group, Array BioPharma Inc., Boulder, CO 80301., Smith D; Structural Biology Group, Array BioPharma Inc., Boulder, CO 80301., Zhang H; Structural Biology Group, Array BioPharma Inc., Boulder, CO 80301., Wang W; Structural Biology and Biochemical and Cellular Pharmacology, Genentech, Inc., South San Francisco, CA 94080., Moffat JG; Structural Biology and Biochemical and Cellular Pharmacology, Genentech, Inc., South San Francisco, CA 94080., Ahn NG; Department of Biochemistry, University of Colorado, Boulder, CO 80305; natalie.ahn@colorado.edu.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Jul 30; Vol. 116 (31), pp. 15463-15468. Date of Electronic Publication: 2019 Jul 16.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1091-6490
DOI:10.1073/pnas.1906824116