First-in-Human Randomized Study to Assess the Safety and Immunogenicity of an Investigational Respiratory Syncytial Virus (RSV) Vaccine Based on Chimpanzee-Adenovirus-155 Viral Vector-Expressing RSV Fusion, Nucleocapsid, and Antitermination Viral Proteins in Healthy Adults.
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| Title: | First-in-Human Randomized Study to Assess the Safety and Immunogenicity of an Investigational Respiratory Syncytial Virus (RSV) Vaccine Based on Chimpanzee-Adenovirus-155 Viral Vector-Expressing RSV Fusion, Nucleocapsid, and Antitermination Viral Proteins in Healthy Adults. |
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| Authors: | Cicconi P; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, United Kingdom., Jones C; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, United Kingdom., Sarkar E; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, United Kingdom., Silva-Reyes L; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, United Kingdom., Klenerman P; Nuffield Department of Medicine, University of Oxford, United Kingdom., de Lara C; Nuffield Department of Medicine, University of Oxford, United Kingdom., Hutchings C; Nuffield Department of Medicine, University of Oxford, United Kingdom., Moris P; GSK, Rixensart, Belgium., Janssens M; GSK, Rixensart, Belgium., Fissette LA; GSK, Wavre, Belgium., Picciolato M; GSK, Rixensart, Belgium., Leach A; GSK, Rockville, Maryland., Gonzalez-Lopez A; GSK, Rockville, Maryland., Dieussaert I; GSK, Rockville, Maryland., Snape MD; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, United Kingdom.; National Institute for Health Research Oxford Biomedical Centre, United Kingdom. |
| Source: | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2020 May 06; Vol. 70 (10), pp. 2073-2081. |
| Publication Type: | Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Oxford University Press Country of Publication: United States NLM ID: 9203213 Publication Model: Print Cited Medium: Internet ISSN: 1537-6591 (Electronic) Linking ISSN: 10584838 NLM ISO Abbreviation: Clin Infect Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1537-6591 |
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| DOI: | 10.1093/cid/ciz653 |