Targeting Pathogenic Lafora Bodies in Lafora Disease Using an Antibody-Enzyme Fusion.

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Title: Targeting Pathogenic Lafora Bodies in Lafora Disease Using an Antibody-Enzyme Fusion.
Authors: Brewer MK; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA., Uittenbogaard A; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA., Austin GL; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA., Segvich DM; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA., DePaoli-Roach A; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Lafora Epilepsy Cure Initiative, University of Kentucky College of Medicine, Lexington, KY 40536, USA., Roach PJ; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Lafora Epilepsy Cure Initiative, University of Kentucky College of Medicine, Lexington, KY 40536, USA., McCarthy JJ; Department of Physiology, University of Kentucky College of Medicine, Lexington, KY 40536, USA., Simmons ZR; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA., Brandon JA; Department of Physiology, University of Kentucky College of Medicine, Lexington, KY 40536, USA., Zhou Z; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA., Zeller J; Northern Biomedical Research, Spring Lake, MI 49456, USA., Young LEA; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA., Sun RC; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA., Pauly JR; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY 40536, USA., Aziz NM; Valerion Therapeutics, Concord, MA 01742, USA., Hodges BL; Valerion Therapeutics, Concord, MA 01742, USA., McKnight TR; Valerion Therapeutics, Concord, MA 01742, USA., Armstrong DD; Valerion Therapeutics, Concord, MA 01742, USA., Gentry MS; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA; Lafora Epilepsy Cure Initiative, University of Kentucky College of Medicine, Lexington, KY 40536, USA; University of Kentucky Epilepsy & Brain Metabolism Alliance, University of Kentucky College of Medicine, Lexington, KY 40536, USA. Electronic address: matthew.gentry@uky.edu.
Source: Cell metabolism [Cell Metab] 2019 Oct 01; Vol. 30 (4), pp. 689-705.e6. Date of Electronic Publication: 2019 Jul 25.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101233170 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-7420 (Electronic) Linking ISSN: 15504131 NLM ISO Abbreviation: Cell Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1932-7420
DOI:10.1016/j.cmet.2019.07.002