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Targeting Pathogenic Lafora Bodies in Lafora Disease Using an Antibody-Enzyme Fusion.

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Title: Targeting Pathogenic Lafora Bodies in Lafora Disease Using an Antibody-Enzyme Fusion.
Authors: Brewer MK; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA., Uittenbogaard A; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA., Austin GL; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA., Segvich DM; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA., DePaoli-Roach A; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Lafora Epilepsy Cure Initiative, University of Kentucky College of Medicine, Lexington, KY 40536, USA., Roach PJ; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Lafora Epilepsy Cure Initiative, University of Kentucky College of Medicine, Lexington, KY 40536, USA., McCarthy JJ; Department of Physiology, University of Kentucky College of Medicine, Lexington, KY 40536, USA., Simmons ZR; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA., Brandon JA; Department of Physiology, University of Kentucky College of Medicine, Lexington, KY 40536, USA., Zhou Z; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA., Zeller J; Northern Biomedical Research, Spring Lake, MI 49456, USA., Young LEA; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA., Sun RC; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA., Pauly JR; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY 40536, USA., Aziz NM; Valerion Therapeutics, Concord, MA 01742, USA., Hodges BL; Valerion Therapeutics, Concord, MA 01742, USA., McKnight TR; Valerion Therapeutics, Concord, MA 01742, USA., Armstrong DD; Valerion Therapeutics, Concord, MA 01742, USA., Gentry MS; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA; Lafora Epilepsy Cure Initiative, University of Kentucky College of Medicine, Lexington, KY 40536, USA; University of Kentucky Epilepsy & Brain Metabolism Alliance, University of Kentucky College of Medicine, Lexington, KY 40536, USA. Electronic address: matthew.gentry@uky.edu.
Source: Cell metabolism [Cell Metab] 2019 Oct 01; Vol. 30 (4), pp. 689-705.e6. Date of Electronic Publication: 2019 Jul 25.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101233170 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-7420 (Electronic) Linking ISSN: 15504131 NLM ISO Abbreviation: Cell Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting Pathogenic Lafora Bodies in Lafora Disease Using an Antibody-Enzyme Fusion.
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  Data: <searchLink fieldCode="AU" term="%22Brewer+MK%22">Brewer MK</searchLink>; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA.<br /><searchLink fieldCode="AU" term="%22Uittenbogaard+A%22">Uittenbogaard A</searchLink>; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA.<br /><searchLink fieldCode="AU" term="%22Austin+GL%22">Austin GL</searchLink>; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA.<br /><searchLink fieldCode="AU" term="%22Segvich+DM%22">Segvich DM</searchLink>; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.<br /><searchLink fieldCode="AU" term="%22DePaoli-Roach+A%22">DePaoli-Roach A</searchLink>; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Lafora Epilepsy Cure Initiative, University of Kentucky College of Medicine, Lexington, KY 40536, USA.<br /><searchLink fieldCode="AU" term="%22Roach+PJ%22">Roach PJ</searchLink>; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Lafora Epilepsy Cure Initiative, University of Kentucky College of Medicine, Lexington, KY 40536, USA.<br /><searchLink fieldCode="AU" term="%22McCarthy+JJ%22">McCarthy JJ</searchLink>; Department of Physiology, University of Kentucky College of Medicine, Lexington, KY 40536, USA.<br /><searchLink fieldCode="AU" term="%22Simmons+ZR%22">Simmons ZR</searchLink>; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA.<br /><searchLink fieldCode="AU" term="%22Brandon+JA%22">Brandon JA</searchLink>; Department of Physiology, University of Kentucky College of Medicine, Lexington, KY 40536, USA.<br /><searchLink fieldCode="AU" term="%22Zhou+Z%22">Zhou Z</searchLink>; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA.<br /><searchLink fieldCode="AU" term="%22Zeller+J%22">Zeller J</searchLink>; Northern Biomedical Research, Spring Lake, MI 49456, USA.<br /><searchLink fieldCode="AU" term="%22Young+LEA%22">Young LEA</searchLink>; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA.<br /><searchLink fieldCode="AU" term="%22Sun+RC%22">Sun RC</searchLink>; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA.<br /><searchLink fieldCode="AU" term="%22Pauly+JR%22">Pauly JR</searchLink>; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY 40536, USA.<br /><searchLink fieldCode="AU" term="%22Aziz+NM%22">Aziz NM</searchLink>; Valerion Therapeutics, Concord, MA 01742, USA.<br /><searchLink fieldCode="AU" term="%22Hodges+BL%22">Hodges BL</searchLink>; Valerion Therapeutics, Concord, MA 01742, USA.<br /><searchLink fieldCode="AU" term="%22McKnight+TR%22">McKnight TR</searchLink>; Valerion Therapeutics, Concord, MA 01742, USA.<br /><searchLink fieldCode="AU" term="%22Armstrong+DD%22">Armstrong DD</searchLink>; Valerion Therapeutics, Concord, MA 01742, USA.<br /><searchLink fieldCode="AU" term="%22Gentry+MS%22">Gentry MS</searchLink>; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA; Lafora Epilepsy Cure Initiative, University of Kentucky College of Medicine, Lexington, KY 40536, USA; University of Kentucky Epilepsy & Brain Metabolism Alliance, University of Kentucky College of Medicine, Lexington, KY 40536, USA. Electronic address: matthew.gentry@uky.edu.
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  Data: <searchLink fieldCode="JN" term="%22101233170%22">Cell metabolism</searchLink> [Cell Metab] 2019 Oct 01; Vol. 30 (4), pp. 689-705.e6. <i>Date of Electronic Publication: </i>2019 Jul 25.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101233170 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1932-7420 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215504131%22">15504131 </searchLink><i>NLM ISO Abbreviation: </i>Cell Metab <i>Subsets: </i>MEDLINE
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