View in EDS HTML Full Text PDF Full Text

Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model.

Saved in:
Bibliographic Details
Title: Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model.
Authors: Spangenberg E; Department of Neurobiology and Behavior, University of California Irvine (UCI), Irvine, CA, 92697, USA., Severson PL; Plexxikon Inc, Berkeley, CA, 94710, USA., Hohsfield LA; Department of Neurobiology and Behavior, University of California Irvine (UCI), Irvine, CA, 92697, USA., Crapser J; Department of Neurobiology and Behavior, University of California Irvine (UCI), Irvine, CA, 92697, USA., Zhang J; Plexxikon Inc, Berkeley, CA, 94710, USA., Burton EA; Plexxikon Inc, Berkeley, CA, 94710, USA., Zhang Y; Plexxikon Inc, Berkeley, CA, 94710, USA., Spevak W; Plexxikon Inc, Berkeley, CA, 94710, USA., Lin J; Plexxikon Inc, Berkeley, CA, 94710, USA., Phan NY; Department of Neurobiology and Behavior, University of California Irvine (UCI), Irvine, CA, 92697, USA., Habets G; Plexxikon Inc, Berkeley, CA, 94710, USA., Rymar A; Plexxikon Inc, Berkeley, CA, 94710, USA., Tsang G; Plexxikon Inc, Berkeley, CA, 94710, USA., Walters J; Plexxikon Inc, Berkeley, CA, 94710, USA., Nespi M; Plexxikon Inc, Berkeley, CA, 94710, USA., Singh P; Plexxikon Inc, Berkeley, CA, 94710, USA., Broome S; Plexxikon Inc, Berkeley, CA, 94710, USA., Ibrahim P; Plexxikon Inc, Berkeley, CA, 94710, USA., Zhang C; Plexxikon Inc, Berkeley, CA, 94710, USA., Bollag G; Plexxikon Inc, Berkeley, CA, 94710, USA., West BL; Plexxikon Inc, Berkeley, CA, 94710, USA., Green KN; Department of Neurobiology and Behavior, University of California Irvine (UCI), Irvine, CA, 92697, USA. kngreen@uci.edu.
Source: Nature communications [Nat Commun] 2019 Aug 21; Vol. 10 (1), pp. 3758. Date of Electronic Publication: 2019 Aug 21.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 31434879
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Spangenberg+E%22">Spangenberg E</searchLink>; Department of Neurobiology and Behavior, University of California Irvine (UCI), Irvine, CA, 92697, USA.<br /><searchLink fieldCode="AU" term="%22Severson+PL%22">Severson PL</searchLink>; Plexxikon Inc, Berkeley, CA, 94710, USA.<br /><searchLink fieldCode="AU" term="%22Hohsfield+LA%22">Hohsfield LA</searchLink>; Department of Neurobiology and Behavior, University of California Irvine (UCI), Irvine, CA, 92697, USA.<br /><searchLink fieldCode="AU" term="%22Crapser+J%22">Crapser J</searchLink>; Department of Neurobiology and Behavior, University of California Irvine (UCI), Irvine, CA, 92697, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Plexxikon Inc, Berkeley, CA, 94710, USA.<br /><searchLink fieldCode="AU" term="%22Burton+EA%22">Burton EA</searchLink>; Plexxikon Inc, Berkeley, CA, 94710, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Plexxikon Inc, Berkeley, CA, 94710, USA.<br /><searchLink fieldCode="AU" term="%22Spevak+W%22">Spevak W</searchLink>; Plexxikon Inc, Berkeley, CA, 94710, USA.<br /><searchLink fieldCode="AU" term="%22Lin+J%22">Lin J</searchLink>; Plexxikon Inc, Berkeley, CA, 94710, USA.<br /><searchLink fieldCode="AU" term="%22Phan+NY%22">Phan NY</searchLink>; Department of Neurobiology and Behavior, University of California Irvine (UCI), Irvine, CA, 92697, USA.<br /><searchLink fieldCode="AU" term="%22Habets+G%22">Habets G</searchLink>; Plexxikon Inc, Berkeley, CA, 94710, USA.<br /><searchLink fieldCode="AU" term="%22Rymar+A%22">Rymar A</searchLink>; Plexxikon Inc, Berkeley, CA, 94710, USA.<br /><searchLink fieldCode="AU" term="%22Tsang+G%22">Tsang G</searchLink>; Plexxikon Inc, Berkeley, CA, 94710, USA.<br /><searchLink fieldCode="AU" term="%22Walters+J%22">Walters J</searchLink>; Plexxikon Inc, Berkeley, CA, 94710, USA.<br /><searchLink fieldCode="AU" term="%22Nespi+M%22">Nespi M</searchLink>; Plexxikon Inc, Berkeley, CA, 94710, USA.<br /><searchLink fieldCode="AU" term="%22Singh+P%22">Singh P</searchLink>; Plexxikon Inc, Berkeley, CA, 94710, USA.<br /><searchLink fieldCode="AU" term="%22Broome+S%22">Broome S</searchLink>; Plexxikon Inc, Berkeley, CA, 94710, USA.<br /><searchLink fieldCode="AU" term="%22Ibrahim+P%22">Ibrahim P</searchLink>; Plexxikon Inc, Berkeley, CA, 94710, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; Plexxikon Inc, Berkeley, CA, 94710, USA.<br /><searchLink fieldCode="AU" term="%22Bollag+G%22">Bollag G</searchLink>; Plexxikon Inc, Berkeley, CA, 94710, USA.<br /><searchLink fieldCode="AU" term="%22West+BL%22">West BL</searchLink>; Plexxikon Inc, Berkeley, CA, 94710, USA.<br /><searchLink fieldCode="AU" term="%22Green+KN%22">Green KN</searchLink>; Department of Neurobiology and Behavior, University of California Irvine (UCI), Irvine, CA, 92697, USA. kngreen@uci.edu.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2019 Aug 21; Vol. 10 (1), pp. 3758. <i>Date of Electronic Publication: </i>2019 Aug 21.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=31434879
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41467-019-11674-z
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 3758
    Titles:
      – TitleFull: Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Spangenberg E
      – PersonEntity:
          Name:
            NameFull: Severson PL
      – PersonEntity:
          Name:
            NameFull: Hohsfield LA
      – PersonEntity:
          Name:
            NameFull: Crapser J
      – PersonEntity:
          Name:
            NameFull: Zhang J
      – PersonEntity:
          Name:
            NameFull: Burton EA
      – PersonEntity:
          Name:
            NameFull: Zhang Y
      – PersonEntity:
          Name:
            NameFull: Spevak W
      – PersonEntity:
          Name:
            NameFull: Lin J
      – PersonEntity:
          Name:
            NameFull: Phan NY
      – PersonEntity:
          Name:
            NameFull: Habets G
      – PersonEntity:
          Name:
            NameFull: Rymar A
      – PersonEntity:
          Name:
            NameFull: Tsang G
      – PersonEntity:
          Name:
            NameFull: Walters J
      – PersonEntity:
          Name:
            NameFull: Nespi M
      – PersonEntity:
          Name:
            NameFull: Singh P
      – PersonEntity:
          Name:
            NameFull: Broome S
      – PersonEntity:
          Name:
            NameFull: Ibrahim P
      – PersonEntity:
          Name:
            NameFull: Zhang C
      – PersonEntity:
          Name:
            NameFull: Bollag G
      – PersonEntity:
          Name:
            NameFull: West BL
      – PersonEntity:
          Name:
            NameFull: Green KN
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 21
              M: 08
              Text: 2019 Aug 21
              Type: published
              Y: 2019
          Identifiers:
            – Type: issn-electronic
              Value: 2041-1723
          Numbering:
            – Type: volume
              Value: 10
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Nature communications
              Type: main
ResultId 1