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CDK7 Inhibition Suppresses Castration-Resistant Prostate Cancer through MED1 Inactivation.

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Title: CDK7 Inhibition Suppresses Castration-Resistant Prostate Cancer through MED1 Inactivation.
Authors: Rasool RU; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Natesan R; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Deng Q; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Aras S; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Lal P; Department of Pathology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Sander Effron S; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Mitchell-Velasquez E; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Posimo JM; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Carskadon S; Department of Urology, Vattikuti Urology Institute, Henry Ford Health System, Detroit, Michigan., Baca SC; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts., Pomerantz MM; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts., Siddiqui J; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan., Schwartz LE; Department of Pathology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Lee DJ; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Palanisamy N; Department of Urology, Vattikuti Urology Institute, Henry Ford Health System, Detroit, Michigan., Narla G; Division of Genetic Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan., Den RB; Department of Radiation Oncology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania., Freedman ML; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts., Brady DC; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Asangani IA; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. asangani@upenn.edu.; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.; Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Source: Cancer discovery [Cancer Discov] 2019 Nov; Vol. 9 (11), pp. 1538-1555. Date of Electronic Publication: 2019 Aug 29.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CDK7 Inhibition Suppresses Castration-Resistant Prostate Cancer through MED1 Inactivation.
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  Data: <searchLink fieldCode="AU" term="%22Rasool+RU%22">Rasool RU</searchLink>; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Natesan+R%22">Natesan R</searchLink>; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Deng+Q%22">Deng Q</searchLink>; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Aras+S%22">Aras S</searchLink>; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Lal+P%22">Lal P</searchLink>; Department of Pathology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Sander+Effron+S%22">Sander Effron S</searchLink>; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Mitchell-Velasquez+E%22">Mitchell-Velasquez E</searchLink>; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Posimo+JM%22">Posimo JM</searchLink>; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Carskadon+S%22">Carskadon S</searchLink>; Department of Urology, Vattikuti Urology Institute, Henry Ford Health System, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Baca+SC%22">Baca SC</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Pomerantz+MM%22">Pomerantz MM</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Siddiqui+J%22">Siddiqui J</searchLink>; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Schwartz+LE%22">Schwartz LE</searchLink>; Department of Pathology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Lee+DJ%22">Lee DJ</searchLink>; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Palanisamy+N%22">Palanisamy N</searchLink>; Department of Urology, Vattikuti Urology Institute, Henry Ford Health System, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Narla+G%22">Narla G</searchLink>; Division of Genetic Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Den+RB%22">Den RB</searchLink>; Department of Radiation Oncology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Freedman+ML%22">Freedman ML</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Brady+DC%22">Brady DC</searchLink>; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Asangani+IA%22">Asangani IA</searchLink>; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. asangani@upenn.edu.; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.; Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
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  Data: <searchLink fieldCode="JN" term="%22101561693%22">Cancer discovery</searchLink> [Cancer Discov] 2019 Nov; Vol. 9 (11), pp. 1538-1555. <i>Date of Electronic Publication: </i>2019 Aug 29.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101561693 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2159-8290 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221598274%22">21598274 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Discov <i>Subsets: </i>MEDLINE
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        Value: 10.1158/2159-8290.CD-19-0189
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      – TitleFull: CDK7 Inhibition Suppresses Castration-Resistant Prostate Cancer through MED1 Inactivation.
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              Text: 2019 Nov
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