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Complement C3 Inhibitor Pegcetacoplan for Geographic Atrophy Secondary to Age-Related Macular Degeneration: A Randomized Phase 2 Trial.

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Title: Complement C3 Inhibitor Pegcetacoplan for Geographic Atrophy Secondary to Age-Related Macular Degeneration: A Randomized Phase 2 Trial.
Authors: Liao DS; Retina-Vitreous Associates Medical Group, Beverly Hills, California. Electronic address: dave_liao@laretina.com., Grossi FV; Apellis Pharmaceuticals, Inc, Waltham, Massachusetts., El Mehdi D; Apellis Pharmaceuticals, Inc, Waltham, Massachusetts., Gerber MR; Apellis Pharmaceuticals, Inc, Waltham, Massachusetts., Brown DM; Vitreoretinal Consultants, Methodist Hospital, Houston, Texas., Heier JS; Ophthalmic Consultants of Boston, Boston, Massachusetts., Wykoff CC; Retina Consultants of Houston, Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas., Singerman LJ; Retina Associates of Cleveland, Cleveland, Ohio., Abraham P; Black Hills Regional Eye Institute, Rapid City, Iowa., Grassmann F; Institute of Human Genetics, University of Regensburg, Regensburg, Germany; Karolinska Institutet, Stockholm, Sweden., Nuernberg P; University of Cologne, Cologne, Germany., Weber BHF; Institute of Human Genetics, University of Regensburg, Regensburg, Germany., Deschatelets P; Apellis Pharmaceuticals, Inc, Waltham, Massachusetts., Kim RY; Apellis Pharmaceuticals, Inc, Waltham, Massachusetts., Chung CY; Apellis Pharmaceuticals, Inc, Waltham, Massachusetts., Ribeiro RM; Apellis Pharmaceuticals, Inc, Waltham, Massachusetts., Hamdani M; Apellis Pharmaceuticals, Inc, Waltham, Massachusetts., Rosenfeld PJ; Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida., Boyer DS; Retina-Vitreous Associates Medical Group, Los Angeles, California., Slakter JS; Vitreous Retina Macula Consultants of New York, New York; New York University School of Medicine, New York, New York., Francois CG; Apellis Pharmaceuticals, Inc, Waltham, Massachusetts.
Source: Ophthalmology [Ophthalmology] 2020 Feb; Vol. 127 (2), pp. 186-195. Date of Electronic Publication: 2019 Jul 16.
Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7802443 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-4713 (Electronic) Linking ISSN: 01616420 NLM ISO Abbreviation: Ophthalmology Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Complement C3 Inhibitor Pegcetacoplan for Geographic Atrophy Secondary to Age-Related Macular Degeneration: A Randomized Phase 2 Trial.
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  Data: <searchLink fieldCode="AU" term="%22Liao+DS%22">Liao DS</searchLink>; Retina-Vitreous Associates Medical Group, Beverly Hills, California. Electronic address: dave_liao@laretina.com.<br /><searchLink fieldCode="AU" term="%22Grossi+FV%22">Grossi FV</searchLink>; Apellis Pharmaceuticals, Inc, Waltham, Massachusetts.<br /><searchLink fieldCode="AU" term="%22El+Mehdi+D%22">El Mehdi D</searchLink>; Apellis Pharmaceuticals, Inc, Waltham, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Gerber+MR%22">Gerber MR</searchLink>; Apellis Pharmaceuticals, Inc, Waltham, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Brown+DM%22">Brown DM</searchLink>; Vitreoretinal Consultants, Methodist Hospital, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Heier+JS%22">Heier JS</searchLink>; Ophthalmic Consultants of Boston, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Wykoff+CC%22">Wykoff CC</searchLink>; Retina Consultants of Houston, Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Singerman+LJ%22">Singerman LJ</searchLink>; Retina Associates of Cleveland, Cleveland, Ohio.<br /><searchLink fieldCode="AU" term="%22Abraham+P%22">Abraham P</searchLink>; Black Hills Regional Eye Institute, Rapid City, Iowa.<br /><searchLink fieldCode="AU" term="%22Grassmann+F%22">Grassmann F</searchLink>; Institute of Human Genetics, University of Regensburg, Regensburg, Germany; Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Nuernberg+P%22">Nuernberg P</searchLink>; University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Weber+BHF%22">Weber BHF</searchLink>; Institute of Human Genetics, University of Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Deschatelets+P%22">Deschatelets P</searchLink>; Apellis Pharmaceuticals, Inc, Waltham, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Kim+RY%22">Kim RY</searchLink>; Apellis Pharmaceuticals, Inc, Waltham, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Chung+CY%22">Chung CY</searchLink>; Apellis Pharmaceuticals, Inc, Waltham, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Ribeiro+RM%22">Ribeiro RM</searchLink>; Apellis Pharmaceuticals, Inc, Waltham, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Hamdani+M%22">Hamdani M</searchLink>; Apellis Pharmaceuticals, Inc, Waltham, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Rosenfeld+PJ%22">Rosenfeld PJ</searchLink>; Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida.<br /><searchLink fieldCode="AU" term="%22Boyer+DS%22">Boyer DS</searchLink>; Retina-Vitreous Associates Medical Group, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Slakter+JS%22">Slakter JS</searchLink>; Vitreous Retina Macula Consultants of New York, New York; New York University School of Medicine, New York, New York.<br /><searchLink fieldCode="AU" term="%22Francois+CG%22">Francois CG</searchLink>; Apellis Pharmaceuticals, Inc, Waltham, Massachusetts.
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  Data: <searchLink fieldCode="JN" term="%227802443%22">Ophthalmology</searchLink> [Ophthalmology] 2020 Feb; Vol. 127 (2), pp. 186-195. <i>Date of Electronic Publication: </i>2019 Jul 16.
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  Data: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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