A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity.
Saved in:
| Title: | A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity. |
|---|---|
| Authors: | Bradfield JP; Center for Applied Genomics, Children's Hospital of Philadelphia, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Quantinuum Research LLC, San Diego, CA, USA., Vogelezang S; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Felix JF; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Chesi A; Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Center for Spatial and Functional Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Helgeland Ø; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Genetics and Bioinformatics, Health Data and Digitalization, Norwegian Institute of Public Health, Oslo, Norway., Horikoshi M; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045, Japan., Karhunen V; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, W2 1PG, UK., Lowry E; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, PO Box 8000, FI-90014 Oulun yliopisto, Finland., Cousminer DL; Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Center for Spatial and Functional Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Genetics, University of Pennsylvania, Philadelphia., Ahluwalia TS; Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital 2820, University of Copenhagen, Copenhagen, Denmark.; Steno Diabetes Center Copenhagen, Gentofte, Denmark.; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Thiering E; Helmholtz Zentrum München-German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany.; Ludwig Maximilians University of Munich, Dr. von Hauner Children's Hospital, Munich, Germany., Boh ET; Saw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore, Singapore., Zafarmand MH; Department of Public Health, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, The Netherlands.; Department of Clinical Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, The Netherlands., Vilor-Tejedor N; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Universitat Pompeu Fabra, Barcelona, Spain.; CIBER de Epidemiología y Salud Pública, Madrid, Spain.; Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, Dr. Aiguader 88, 08003 Barcelona, Spain.; BarcelonaBeta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain., Wang CA; School of Medicine and Public Health, Faculty of Medicine and Health, The University of Newcastle., Joro R; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Finland., Chen Z; Department of Preventive Medicine, University of Southern California, Los Angeles, California, USA., Gauderman WJ; Department of Preventive Medicine, University of Southern California, Los Angeles, California, USA., Pitkänen N; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku 20521, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku 20014, Finland., Parra EJ; Department of Anthropology, University of Toronto at Mississauga, Mississauga, ON, Canada., Fernandez-Rhodes L; Department of Biobehavioral Health, Pennsylvania State University.; Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Alyass A; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada., Monnereau C; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Curtin JA; Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, Manchester University NHS Foundation Trust., Have CT; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., McCormack SE; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Endocrinology and Diabetes, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., Hollensted M; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Frithioff-Bøjsøe C; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; The Children's Obesity Clinic, Department of Pediatrics, Copenhagen University Hospital Holbæk, Holbæk, Denmark., Valladares-Salgado A; Unidad de Investigacion Medica en Bioquımica, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico., Peralta-Romero J; Unidad de Investigacion Medica en Bioquımica, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico., Teo YY; Saw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore, Singapore.; NUS Graduate School for Integrative Science and Engineering, National University of Singapore, Singapore, 119077, Singapore.; Department of Statistics and Applied Probability, National University of Singapore, Singapore, Singapore.; Life Sciences Institute, National University of Singapore, Singapore, 117456, Singapore.; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, 138672, Singapore., Standl M; Helmholtz Zentrum München-German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany., Leinonen JT; Institute for Molecular Medicine Finland, FIMM, University of Helsinki, Finland., Holm JC; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; The Children's Obesity Clinic, Department of Pediatrics, Copenhagen University Hospital Holbæk, Holbæk, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Peters T; Department of Child and Adolescent Psychiatry, University Hospital Essen, University of Duisburg-Essen, Germany., Vioque J; CIBER de Epidemiología y Salud Pública, Madrid, Spain.; University Miguel Hernandez, Alicante, Spain.; ISABIAL-FISABIO Foundation, Alicante, Spain., Vrijheid M; ISGlobal, Institute for Global Health, Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain.; CIBER de Epidemiología y Salud Pública, Madrid, Spain., Simpson A; Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, Manchester University NHS Foundation Trust., Custovic A; Department of Paediatrics, Imperial College London, UK., Vaudel M; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway., Canouil M; CNRS UMR 8199, European Genomic Institute for Diabetes, Institut Pasteur de Lille, University of Lille, Lille, France., Lindi V; University of Eastern Finland Library, Kuopio, Finland., Atalay M; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Finland., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere 33521, Finland.; Department of Clinical Physiology, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere 33014, Finland., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku 20521, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku 20014, Finland.; Centre for Population Health Research, University of Turku and Turku University Hospital, Finland., van Schaik BDC; Department of Clinical Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, The Netherlands., Berkowitz RI; Department of Child and Adolescent Psychiatry and Behavioral Sciences, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Cole SA; Texas Biomedical Research Institute, San Antonio, TX., Voruganti VS; Department of Nutrition and Nutrition Research Institute, University of North Carolina at Chapel Hill., Wang Y; Department of Epidemiology, University of North Carolina at Chapel Hill., Highland HM; Department of Epidemiology, University of North Carolina at Chapel Hill., Comuzzie AG; The Obesity Society., Butte NF; Department of Pediatrics, Baylor College of Medicine., Justice AE; Department of Epidemiology, University of North Carolina at Chapel Hill.; Biomedical and Translational Informatics, Geisinger Health System., Gahagan S; Center for Community Health, Department of Pediatrics, University of California at San Diego., Blanco E; Center for Community Health, Department of Pediatrics, University of California at San Diego., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33520, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere 33014, Finland., Lakka TA; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Hebebrand J; Department of Child and Adolescent Psychiatry, University Hospital Essen, University of Duisburg-Essen, Germany., Bonnefond A; CNRS UMR 8199, European Genomic Institute for Diabetes, Institut Pasteur de Lille, University of Lille, Lille, France.; Department of Medicine, Section of Genomics of Common Disease, Imperial College London, London, UK., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Froguel P; CNRS UMR 8199, European Genomic Institute for Diabetes, Institut Pasteur de Lille, University of Lille, Lille, France.; Department of Medicine, Section of Genomics of Common Disease, Imperial College London, London, UK., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33520, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere 33014, Finland.; Department of Cardiology, Heart Center, Tampere University Hospital, Tampere 33521, Finland., Cruz M; Unidad de Investigacion Medica en Bioquımica, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico., Kobes S; Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes Digestive and Kidney Diseases, NIH, USA., Hanson RL; Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes Digestive and Kidney Diseases, NIH, USA., Zemel BS; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Gastroenterology, Hepatology and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., Hinney A; Department of Child and Adolescent Psychiatry, University Hospital Essen, University of Duisburg-Essen, Germany., Teo KK; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.; Department of Medicine, McMaster University, Hamilton, ON, Canada., Meyre D; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada., North KE; Department of Epidemiology, University of North Carolina at Chapel Hill.; Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill., Gilliland FD; Department of Preventive Medicine, University of Southern California, Los Angeles, California, USA., Bisgaard H; Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital 2820, University of Copenhagen, Copenhagen, Denmark., Bustamante M; ISGlobal, Institute for Global Health, Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain.; CIBER de Epidemiología y Salud Pública, Madrid, Spain., Bonnelykke K; Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital 2820, University of Copenhagen, Copenhagen, Denmark., Pennell CE; School of Medicine and Public Health, Faculty of Medicine and Health, The University of Newcastle., Rivadeneira F; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands., Uitterlinden AG; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands., Baier LJ; Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes Digestive and Kidney Diseases, NIH, USA., Vrijkotte TGM; Department of Public Health, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, The Netherlands., Heinrich J; Helmholtz Zentrum München-German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany.; Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Ludwig Maximilians University of Munich, University Hospital Munich, Munich, Germany.; Allergy and Lung Health Unit, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia., Sørensen TIA; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Public Health, Section of Epidemiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Medical Research Council Integrative Epidemiology Unit, Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 2BN, UK., Saw SM; Saw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore, Singapore.; Singapore Eye Research Institute, Singapore, Singapore., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Eriksson J; Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Folkhälsan Research Center, Helsink Finland.; Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland., Widén E; Institute for Molecular Medicine Finland, FIMM, University of Helsinki, Finland., McCarthy MI; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford OX3 9DU., Njølstad PR; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Pediatrics and Adolescents, Haukeland University Hospital, Bergen, Norway., Power C; Population, Policy and Practice, UCL Great Ormond Street Institute of Child Health, University College London, London, UK., Hyppönen E; Population, Policy and Practice, UCL Great Ormond Street Institute of Child Health, University College London, London, UK.; Australian Centre for Precision Health, University of South Australia Cancer Research Institute, Adelaide, Australia.; South Australian Health and Medical Research Institute, Adelaide, Australia., Sebert S; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, PO Box 8000, FI-90014 Oulun yliopisto, Finland.; Biocenter Oulu, University of Oulu, Aapistie 5, 90220 Oulu, Finland.; Department for Genomics of Common Diseases, School of Medicine, Imperial College London, UK., Brown CD; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Järvelin MR; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, W2 1PG, UK.; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, PO Box 8000, FI-90014 Oulun yliopisto, Finland.; Biocenter Oulu, University of Oulu, Aapistie 5, 90220 Oulu, Finland.; Unit of Primary Health Care, Oulu University Hospital, OYS, Kajaanintie 50, 90220 Oulu, Finland.; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, Kingston Lane, Uxbridge, Middlesex UB8 3PH, UK., Timpson NJ; Medical Research Council Integrative Epidemiology Unit, Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 2BN, UK., Johansson S; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Medical Genetics, Haukeland University Hospital, Bergen, Norway., Hakonarson H; Center for Applied Genomics, Children's Hospital of Philadelphia, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Human Genetics, Department of Pediatrics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Jaddoe VWV; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Grant SFA |
| Corporate Authors: | Early Growth Genetics Consortium |
| Source: | Human molecular genetics [Hum Mol Genet] 2019 Oct 01; Vol. 28 (19), pp. 3327-3338. |
| Publication Type: | Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| ISSN: | 1460-2083 |
|---|---|
| DOI: | 10.1093/hmg/ddz161 |
