NPC1 regulates ER contacts with endocytic organelles to mediate cholesterol egress.

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Title: NPC1 regulates ER contacts with endocytic organelles to mediate cholesterol egress.
Authors: Höglinger D; Department of Pharmacology, University of Oxford, Oxford, UK.; Heidelberg University Biochemistry Center (BZH), Heidelberg, Germany., Burgoyne T; UCL Institute of Ophthalmology, London, UK.; Paediatric Respiratory Department, Royal Brompton Hospital, London, UK., Sanchez-Heras E; UCL Institute of Ophthalmology, London, UK., Hartwig P; Heidelberg University Biochemistry Center (BZH), Heidelberg, Germany., Colaco A; Department of Pharmacology, University of Oxford, Oxford, UK.; Center for Autophagy, Recycling and Disease, Danish Cancer Society Research Center, Copenhagen, Denmark., Newton J; Department of Biochemistry and Molecular Biology, Virginia Commonwealth University School of Medicine, Richmond, VA, 23298, USA., Futter CE; UCL Institute of Ophthalmology, London, UK., Spiegel S; Department of Biochemistry and Molecular Biology, Virginia Commonwealth University School of Medicine, Richmond, VA, 23298, USA., Platt FM; Department of Pharmacology, University of Oxford, Oxford, UK., Eden ER; UCL Institute of Ophthalmology, London, UK. e.eden@ucl.ac.uk.
Source: Nature communications [Nat Commun] 2019 Sep 19; Vol. 10 (1), pp. 4276. Date of Electronic Publication: 2019 Sep 19.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-019-12152-2