Extensive genomic recoding by codon-pair deoptimization selective for mammals is a flexible tool to generate attenuated vaccine candidates for dengue virus 2.

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Title: Extensive genomic recoding by codon-pair deoptimization selective for mammals is a flexible tool to generate attenuated vaccine candidates for dengue virus 2.
Authors: Stauft CB; Department of Molecular Genetics and Microbiology, Stony Brook University School of Medicine, Stony Brook, NY, USA. Electronic address: charles.stauft@stonybrook.edu., Song Y; Department of Molecular Genetics and Microbiology, Stony Brook University School of Medicine, Stony Brook, NY, USA. Electronic address: yutong.song@stonybrook.edu., Gorbatsevych O; Department of Molecular Genetics and Microbiology, Stony Brook University School of Medicine, Stony Brook, NY, USA. Electronic address: oleksandr.gorbatsevych@stonybrook.edu., Pantoja P; Unit of Comparative Medicine, Virology Laboratory, Caribbean Primate Research Center, University of Puerto Rico, San Juan, PR, USA. Electronic address: petraleigh.pantoja@upr.edu., Rodriguez IV; Unit of Comparative Medicine, Virology Laboratory, Caribbean Primate Research Center, University of Puerto Rico, San Juan, PR, USA. Electronic address: idia.rodriguez1@upr.edu., Futcher B; Department of Molecular Genetics and Microbiology, Stony Brook University School of Medicine, Stony Brook, NY, USA. Electronic address: bruce.futcher@stonybrook.edu., Sariol CA; Unit of Comparative Medicine, Virology Laboratory, Caribbean Primate Research Center, University of Puerto Rico, San Juan, PR, USA. Electronic address: carlos.sariol1@upr.edu., Wimmer E; Department of Molecular Genetics and Microbiology, Stony Brook University School of Medicine, Stony Brook, NY, USA. Electronic address: eckard.wimmer@stonybrook.edu.
Source: Virology [Virology] 2019 Nov; Vol. 537, pp. 237-245. Date of Electronic Publication: 2019 Sep 05.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 0110674 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0341 (Electronic) Linking ISSN: 00426822 NLM ISO Abbreviation: Virology Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1096-0341
DOI:10.1016/j.virol.2019.09.003