Integrated paired-end enhancer profiling and whole-genome sequencing reveals recurrent CCNE1 and IGF2 enhancer hijacking in primary gastric adenocarcinoma.

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Title: Integrated paired-end enhancer profiling and whole-genome sequencing reveals recurrent CCNE1 and IGF2 enhancer hijacking in primary gastric adenocarcinoma.
Authors: Ooi WF; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore., Nargund AM; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore., Lim KJ; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.; Centre for Computational Biology, Duke-NUS Medical School, Singapore., Zhang S; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore., Xing M; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore., Mandoli A; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore., Lim JQ; Lymphoma Genomic Translational Laboratory, National Cancer Centre Singapore, Singapore., Ho SWT; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Guo Y; Computational and Systems Biology, Genome Institute of Singapore, Singapore., Yao X; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore., Lin SJ; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore., Nandi T; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore., Xu C; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore., Ong X; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore., Lee M; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore., Tan AL; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore., Lam YN; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore., Teo JX; SingHealth/Duke-NUS Institute of Precision Medicine, National Heart Centre, Singapore., Kaneda A; Department of Molecular Oncology, Chiba University, Chiba, Japan., White KP; Institute for Genomics and Systems Biology, University of Chicago and Argonne National Laboratory, Chicago, Illinois, USA.; Tempus Labs, Chicago, Illinois, USA., Lim WK; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.; SingHealth/Duke-NUS Institute of Precision Medicine, National Heart Centre, Singapore., Rozen SG; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.; Centre for Computational Biology, Duke-NUS Medical School, Singapore.; SingHealth/Duke-NUS Institute of Precision Medicine, National Heart Centre, Singapore., Teh BT; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore.; SingHealth/Duke-NUS Institute of Precision Medicine, National Heart Centre, Singapore.; Laboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore., Li S; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore., Skanderup AJ; Computational and Systems Biology, Genome Institute of Singapore, Singapore., Tan P; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore gmstanp@duke-nus.edu.sg.; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore.; SingHealth/Duke-NUS Institute of Precision Medicine, National Heart Centre, Singapore.
Source: Gut [Gut] 2020 Jun; Vol. 69 (6), pp. 1039-1052. Date of Electronic Publication: 2019 Sep 21.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: British Medical Assn Country of Publication: England NLM ID: 2985108R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-3288 (Electronic) Linking ISSN: 00175749 NLM ISO Abbreviation: Gut Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1468-3288
DOI:10.1136/gutjnl-2018-317612