Determination of Cytochrome P450 Isoenzyme 2D6 (CYP2D6) Genotypes and Pharmacogenomic Impact on Primaquine Metabolism in an Active-Duty US Military Population.
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| Title: | Determination of Cytochrome P450 Isoenzyme 2D6 (CYP2D6) Genotypes and Pharmacogenomic Impact on Primaquine Metabolism in an Active-Duty US Military Population. |
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| Authors: | Spring MD; Department of Bacterial and Parasitic Diseases, US Army Medical Directorate of the Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Silver Spring., Sousa JC; Experimental Therapeutics Branch, Silver Spring., Li Q; Experimental Therapeutics Branch, Silver Spring., Darko CA; General Dynamics Information Technology, Silver Spring., Morrison MN; Clinical Trials Center, Silver Spring., Marcsisin SR; Food and Drug Administration, Boston, Massachusetts., Mills KT; Davita Medical Group, Colorado Springs, Colorado., Potter BM; Experimental Therapeutics Branch, Silver Spring., Paolino KM; Division of Infectious Disease, SUNY Upstate Medical University, Syracuse, New York., Twomey PS; Licensing and Early Development-Oncology, Genentech, South San Francisco, California., Moon JE; Malaria Vaccine Branch, Silver Spring., Tosh DM; Clinical Operations, Government and Public Health Solutions, ICON, Hinckley, Ohio., Cicatelli SB; Clinical Trials Center, Silver Spring., Froude JW; Vaccines/Therapeutics Division, Defense Threat Reduction Agency, Fort Belvoir, Virginia., Pybus BS; Experimental Therapeutics Branch, Silver Spring., Oliver TG; Clinical Pharamacology Division, Silver Spring., McCarthy WF; U. S. Army Medical Materiel Development Activity, Fort Detrick, Maryland., Waters NC; Department of Bacterial and Parasitic Diseases, US Army Medical Directorate of the Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand., Smith PL; Center for Enabling Capabilities, Silver Spring., Reichard GA; Experimental Therapeutics Branch, Silver Spring., Bennett JW; Infectious Diseases Division, Department of Medicine, Uniformed Services University of the Health Sciences, Silver Spring.; Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring. |
| Source: | The Journal of infectious diseases [J Infect Dis] 2019 Oct 22; Vol. 220 (11), pp. 1761-1770. |
| Publication Type: | Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: Oxford University Press Country of Publication: United States NLM ID: 0413675 Publication Model: Print Cited Medium: Internet ISSN: 1537-6613 (Electronic) Linking ISSN: 00221899 NLM ISO Abbreviation: J Infect Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1537-6613 |
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| DOI: | 10.1093/infdis/jiz386 |
