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What Makes Polysorbate Functional? Impact of Polysorbate 80 Grade and Quality on IgG Stability During Mechanical Stress.

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Title: What Makes Polysorbate Functional? Impact of Polysorbate 80 Grade and Quality on IgG Stability During Mechanical Stress.
Authors: Grabarek AD; Coriolis Pharma Research, Fraunhoferstr. 18b, 82152 Martinsried, Germany; Division of BioTherapeutics, Leiden Academic Centre for Drug Research (LACDR), Leiden University, PO Box 9502, 2300 RA Leiden, The Netherlands., Bozic U; Coriolis Pharma Research, Fraunhoferstr. 18b, 82152 Martinsried, Germany., Rousel J; Coriolis Pharma Research, Fraunhoferstr. 18b, 82152 Martinsried, Germany; Division of BioTherapeutics, Leiden Academic Centre for Drug Research (LACDR), Leiden University, PO Box 9502, 2300 RA Leiden, The Netherlands., Menzen T; Coriolis Pharma Research, Fraunhoferstr. 18b, 82152 Martinsried, Germany., Kranz W; Coriolis Pharma Research, Fraunhoferstr. 18b, 82152 Martinsried, Germany., Wuchner K; Janssen Research & Development, Pharmaceutical Development & Manufacturing Sciences, Large Molecule Analytical Development, Schaffhausen, Switzerland., Jiskoot W; Coriolis Pharma Research, Fraunhoferstr. 18b, 82152 Martinsried, Germany; Division of BioTherapeutics, Leiden Academic Centre for Drug Research (LACDR), Leiden University, PO Box 9502, 2300 RA Leiden, The Netherlands., Hawe A; Coriolis Pharma Research, Fraunhoferstr. 18b, 82152 Martinsried, Germany. Electronic address: andrea.hawe@coriolis-pharma.com.
Source: Journal of pharmaceutical sciences [J Pharm Sci] 2020 Jan; Vol. 109 (1), pp. 871-880. Date of Electronic Publication: 2019 Oct 12.
Publication Type: Comparative Study; Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6017 (Electronic) Linking ISSN: 00223549 NLM ISO Abbreviation: J Pharm Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1520-6017
DOI:10.1016/j.xphs.2019.10.015