Intrabacterial Metabolism Obscures the Successful Prediction of an InhA Inhibitor of Mycobacterium tuberculosis.

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Bibliographic Details
Title: Intrabacterial Metabolism Obscures the Successful Prediction of an InhA Inhibitor of Mycobacterium tuberculosis.
Authors: Wang X; Department of Pharmacology, Physiology, and Neuroscience , Rutgers University-New Jersey Medical School , Medical Sciences Building, 185 South Orange Avenue , Newark , New Jersey 07103 , United States., Perryman AL; Department of Pharmacology, Physiology, and Neuroscience , Rutgers University-New Jersey Medical School , Medical Sciences Building, 185 South Orange Avenue , Newark , New Jersey 07103 , United States., Li SG; Department of Pharmacology, Physiology, and Neuroscience , Rutgers University-New Jersey Medical School , Medical Sciences Building, 185 South Orange Avenue , Newark , New Jersey 07103 , United States., Paget SD; Department of Pharmacology, Physiology, and Neuroscience , Rutgers University-New Jersey Medical School , Medical Sciences Building, 185 South Orange Avenue , Newark , New Jersey 07103 , United States., Stratton TP; Department of Pharmacology, Physiology, and Neuroscience , Rutgers University-New Jersey Medical School , Medical Sciences Building, 185 South Orange Avenue , Newark , New Jersey 07103 , United States., Lemenze A; Division of Infectious Disease, Department of Medicine, and the Ruy V. Lourenço Center for the Study of Emerging and Reemerging Pathogens , Rutgers University-New Jersey Medical School , Medical Sciences Building, 185 South Orange Avenue , Newark , New Jersey 07103 , United States., Olson AJ; Department of Integrative Structural and Computational Biology , The Scripps Research Institute , Room MB112/Mail Drop MB5, 10550 North Torrey Pines Road , La Jolla , California 92037 , United States., Ekins S; Collaborations in Chemistry , 5616 Hilltop Needmore Road , Fuquay-Varina , North Carolina 27526 , United States., Kumar P; Division of Infectious Disease, Department of Medicine, and the Ruy V. Lourenço Center for the Study of Emerging and Reemerging Pathogens , Rutgers University-New Jersey Medical School , Medical Sciences Building, 185 South Orange Avenue , Newark , New Jersey 07103 , United States., Freundlich JS; Department of Pharmacology, Physiology, and Neuroscience , Rutgers University-New Jersey Medical School , Medical Sciences Building, 185 South Orange Avenue , Newark , New Jersey 07103 , United States.; Division of Infectious Disease, Department of Medicine, and the Ruy V. Lourenço Center for the Study of Emerging and Reemerging Pathogens , Rutgers University-New Jersey Medical School , Medical Sciences Building, 185 South Orange Avenue , Newark , New Jersey 07103 , United States.
Source: ACS infectious diseases [ACS Infect Dis] 2019 Dec 13; Vol. 5 (12), pp. 2148-2163. Date of Electronic Publication: 2019 Nov 05.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2373-8227
DOI:10.1021/acsinfecdis.9b00295