Physiologically-Based Pharmacokinetic Models for Evaluating Membrane Transporter Mediated Drug-Drug Interactions: Current Capabilities, Case Studies, Future Opportunities, and Recommendations.
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| Title: | Physiologically-Based Pharmacokinetic Models for Evaluating Membrane Transporter Mediated Drug-Drug Interactions: Current Capabilities, Case Studies, Future Opportunities, and Recommendations. |
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| Authors: | Taskar KS; GlaxoSmithKline, DMPK, In Vitro In Vivo Translation, GSK R&D, Ware, UK., Pilla Reddy V; AstraZeneca, Modelling and Simulation, Early Oncology DMPK, Oncology R&D, AstraZeneca, Cambridge, UK., Burt H; Simcyp-Division, Certara UK Ltd., Sheffield, UK., Posada MM; Eli Lilly & Company, Indianapolis, Indiana, USA., Varma M; Pfizer Inc., Groton, Connecticut, USA., Zheng M; Bristol-Myers Squibb Company, Princeton, New Jersey, USA., Ullah M; Roche Innovation Center, Basel, Switzerland., Emami Riedmaier A; AbbVie Inc., North Chicago, Illinois, USA., Umehara KI; Roche Innovation Center, Basel, Switzerland., Snoeys J; Janssen Research and Development, Beerse, Belgium., Nakakariya M; Takeda Pharmaceutical Company Ltd., Kanagawa, Japan., Chu X; Merck Sharp & Dohme Corp., Kenilworth, New Jersey, USA., Beneton M; Servier, Centre-Val de Loire, France., Chen Y; Genentech, San Francisco, California, USA., Huth F; Novartis, Basel, Switzerland., Narayanan R; Shire, Lexington, Massachusetts, USA., Mukherjee D; AbbVie Inc., North Chicago, Illinois, USA., Dixit V; Eisai Inc., Woodliff Lake, New Jersey, USA., Sugiyama Y; Sugiyama Laboratory, Riken, Yokohama, Japan., Neuhoff S; Simcyp-Division, Certara UK Ltd., Sheffield, UK. |
| Source: | Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2020 May; Vol. 107 (5), pp. 1082-1115. Date of Electronic Publication: 2019 Dec 31. |
| Publication Type: | Journal Article; Review |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 31628859 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Physiologically-Based Pharmacokinetic Models for Evaluating Membrane Transporter Mediated Drug-Drug Interactions: Current Capabilities, Case Studies, Future Opportunities, and Recommendations. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Taskar+KS%22">Taskar KS</searchLink>; GlaxoSmithKline, DMPK, In Vitro In Vivo Translation, GSK R&D, Ware, UK.<br /><searchLink fieldCode="AU" term="%22Pilla+Reddy+V%22">Pilla Reddy V</searchLink>; AstraZeneca, Modelling and Simulation, Early Oncology DMPK, Oncology R&D, AstraZeneca, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Burt+H%22">Burt H</searchLink>; Simcyp-Division, Certara UK Ltd., Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Posada+MM%22">Posada MM</searchLink>; Eli Lilly & Company, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Varma+M%22">Varma M</searchLink>; Pfizer Inc., Groton, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Zheng+M%22">Zheng M</searchLink>; Bristol-Myers Squibb Company, Princeton, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Ullah+M%22">Ullah M</searchLink>; Roche Innovation Center, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Emami+Riedmaier+A%22">Emami Riedmaier A</searchLink>; AbbVie Inc., North Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Umehara+KI%22">Umehara KI</searchLink>; Roche Innovation Center, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Snoeys+J%22">Snoeys J</searchLink>; Janssen Research and Development, Beerse, Belgium.<br /><searchLink fieldCode="AU" term="%22Nakakariya+M%22">Nakakariya M</searchLink>; Takeda Pharmaceutical Company Ltd., Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Chu+X%22">Chu X</searchLink>; Merck Sharp & Dohme Corp., Kenilworth, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Beneton+M%22">Beneton M</searchLink>; Servier, Centre-Val de Loire, France.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Genentech, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Huth+F%22">Huth F</searchLink>; Novartis, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Narayanan+R%22">Narayanan R</searchLink>; Shire, Lexington, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Mukherjee+D%22">Mukherjee D</searchLink>; AbbVie Inc., North Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Dixit+V%22">Dixit V</searchLink>; Eisai Inc., Woodliff Lake, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Sugiyama+Y%22">Sugiyama Y</searchLink>; Sugiyama Laboratory, Riken, Yokohama, Japan.<br /><searchLink fieldCode="AU" term="%22Neuhoff+S%22">Neuhoff S</searchLink>; Simcyp-Division, Certara UK Ltd., Sheffield, UK. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220372741%22">Clinical pharmacology and therapeutics</searchLink> [Clin Pharmacol Ther] 2020 May; Vol. 107 (5), pp. 1082-1115. <i>Date of Electronic Publication: </i>2019 Dec 31. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Review – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0372741 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-6535 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200099236%22">00099236 </searchLink><i>NLM ISO Abbreviation: </i>Clin Pharmacol Ther <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=31628859 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/cpt.1693 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1082 Titles: – TitleFull: Physiologically-Based Pharmacokinetic Models for Evaluating Membrane Transporter Mediated Drug-Drug Interactions: Current Capabilities, Case Studies, Future Opportunities, and Recommendations. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Taskar KS – PersonEntity: Name: NameFull: Pilla Reddy V – PersonEntity: Name: NameFull: Burt H – PersonEntity: Name: NameFull: Posada MM – PersonEntity: Name: NameFull: Varma M – PersonEntity: Name: NameFull: Zheng M – PersonEntity: Name: NameFull: Ullah M – PersonEntity: Name: NameFull: Emami Riedmaier A – PersonEntity: Name: NameFull: Umehara KI – PersonEntity: Name: NameFull: Snoeys J – PersonEntity: Name: NameFull: Nakakariya M – PersonEntity: Name: NameFull: Chu X – PersonEntity: Name: NameFull: Beneton M – PersonEntity: Name: NameFull: Chen Y – PersonEntity: Name: NameFull: Huth F – PersonEntity: Name: NameFull: Narayanan R – PersonEntity: Name: NameFull: Mukherjee D – PersonEntity: Name: NameFull: Dixit V – PersonEntity: Name: NameFull: Sugiyama Y – PersonEntity: Name: NameFull: Neuhoff S IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: 2020 May Type: published Y: 2020 Identifiers: – Type: issn-electronic Value: 1532-6535 Numbering: – Type: volume Value: 107 – Type: issue Value: 5 Titles: – TitleFull: Clinical pharmacology and therapeutics Type: main |
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