Virtual screening identified compounds that bind to cyclin dependent kinase 2 and prevent herpes simplex virus type 1 replication and reactivation in neurons.
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| Title: | Virtual screening identified compounds that bind to cyclin dependent kinase 2 and prevent herpes simplex virus type 1 replication and reactivation in neurons. |
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| Authors: | Viegas DJ; NUPEM, Instituto de Biodiversidade e Sustentabilidade, Universidade Federal do Rio de Janeiro, NUPEM. Av. São José do Barreto, 764, São José do Barreto, Macaé, RJ, CEP 27965-045, Brazil., Edwards TG; College of Medicine, Department of Molecular Genetics and Microbiology University of Florida, Gainesville, FL, 32610-0266, USA., Bloom DC; College of Medicine, Department of Molecular Genetics and Microbiology University of Florida, Gainesville, FL, 32610-0266, USA., Abreu PA; NUPEM, Instituto de Biodiversidade e Sustentabilidade, Universidade Federal do Rio de Janeiro, NUPEM. Av. São José do Barreto, 764, São José do Barreto, Macaé, RJ, CEP 27965-045, Brazil. Electronic address: paulaabreu@macae.ufrj.br. |
| Source: | Antiviral research [Antiviral Res] 2019 Dec; Vol. 172, pp. 104621. Date of Electronic Publication: 2019 Oct 18. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8109699 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9096 (Electronic) Linking ISSN: 01663542 NLM ISO Abbreviation: Antiviral Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1872-9096 |
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| DOI: | 10.1016/j.antiviral.2019.104621 |
