Cephalosporin nitric oxide-donor prodrug DEA-C3D disperses biofilms formed by clinical cystic fibrosis isolates of Pseudomonas aeruginosa.

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Title: Cephalosporin nitric oxide-donor prodrug DEA-C3D disperses biofilms formed by clinical cystic fibrosis isolates of Pseudomonas aeruginosa.
Authors: Soren O; National Biofilms Innovation Centre, University of Southampton, Southampton SO17 1BJ, UK.; Biological Sciences and Institute for Life Sciences, University of Southampton, Southampton SO17 1BJ, UK., Rineh A; Molecular Horizons and School of Chemistry & Molecular Bioscience, University of Wollongong, NSW, 2522, Australia.; Illawarra Health & Medical Research Institute, Wollongong, NSW, 2522, Australia., Silva DG; National Biofilms Innovation Centre, University of Southampton, Southampton SO17 1BJ, UK.; Faculty of Medicine and Institute for Life Sciences, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK., Cai Y; National Biofilms Innovation Centre, University of Southampton, Southampton SO17 1BJ, UK.; Biological Sciences and Institute for Life Sciences, University of Southampton, Southampton SO17 1BJ, UK., Howlin RP; Biological Sciences and Institute for Life Sciences, University of Southampton, Southampton SO17 1BJ, UK.; NIHR Southampton Clinical Research Facility and NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation, Southampton SO16 6YD, UK., Allan RN; National Biofilms Innovation Centre, University of Southampton, Southampton SO17 1BJ, UK.; Biological Sciences and Institute for Life Sciences, University of Southampton, Southampton SO17 1BJ, UK.; NIHR Southampton Clinical Research Facility and NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation, Southampton SO16 6YD, UK., Feelisch M; Faculty of Medicine and Institute for Life Sciences, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK., Davies JC; Cystic Fibrosis Trust Strategic Research Centre and National Heart and Lung Institute, Imperial College London, London SW3 6LY, UK., Connett GJ; National Biofilms Innovation Centre, University of Southampton, Southampton SO17 1BJ, UK.; Faculty of Medicine and Institute for Life Sciences, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.; NIHR Southampton Clinical Research Facility and NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation, Southampton SO16 6YD, UK., Faust SN; National Biofilms Innovation Centre, University of Southampton, Southampton SO17 1BJ, UK.; Faculty of Medicine and Institute for Life Sciences, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.; NIHR Southampton Clinical Research Facility and NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation, Southampton SO16 6YD, UK., Kelso MJ; Molecular Horizons and School of Chemistry & Molecular Bioscience, University of Wollongong, NSW, 2522, Australia.; Illawarra Health & Medical Research Institute, Wollongong, NSW, 2522, Australia., Webb JS; National Biofilms Innovation Centre, University of Southampton, Southampton SO17 1BJ, UK.; Biological Sciences and Institute for Life Sciences, University of Southampton, Southampton SO17 1BJ, UK.; NIHR Southampton Clinical Research Facility and NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation, Southampton SO16 6YD, UK.
Source: The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 2020 Jan 01; Vol. 75 (1), pp. 117-125.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 7513617 Publication Model: Print Cited Medium: Internet ISSN: 1460-2091 (Electronic) Linking ISSN: 03057453 NLM ISO Abbreviation: J Antimicrob Chemother Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1460-2091
DOI:10.1093/jac/dkz378