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KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2.

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Title: KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2.
Authors: Spiombi E; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy.; Department of Medical Biotechnology and Translational Medicine, University of Milan, 20090, Segrate, Milan, Italy., Angrisani A; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy., Fonte S; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy., De Feudis G; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy.; Department of Experimental Oncology, European Institute of Oncology, 20139, Milan, Italy., Fabretti F; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy., Cucchi D; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy.; Barts Cancer Institute, Queen Mary University of London, Centre for Molecular Oncology, John Vane Science Center, London, EC1M 6BQ, UK., Izzo M; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy.; Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, 00161, Rome, Italy., Infante P; Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, 00161, Rome, Italy., Miele E; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy.; Department of Hematology/Oncology and Stem Cell Transplantation, Bambino Gesù Children's Hospital, IRCCS, 00165, Rome, Italy., Po A; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy., Di Magno L; Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, 00161, Rome, Italy., Magliozzi R; Kymab ltd, Babraham Campus, Cambridge, CB22 3AT, UK., Guardavaccaro D; Department of Biotechnology, University of Verona, Verona, Italy., Maroder M; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy., Canettieri G; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy.; Istituto Pasteur, Fondazione Cenci-Bolognetti, Sapienza University of Rome, 00161, Rome, Italy., Giannini G; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy.; Istituto Pasteur, Fondazione Cenci-Bolognetti, Sapienza University of Rome, 00161, Rome, Italy., Ferretti E; Department of Experimental Medicine, Sapienza University, 00161, Rome, Italy., Gulino A; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy., Di Marcotullio L; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy.; Istituto Pasteur, Fondazione Cenci-Bolognetti, Sapienza University of Rome, 00161, Rome, Italy., Moretti M; Department of Experimental Medicine, Sapienza University, 00161, Rome, Italy., De Smaele E; Department of Experimental Medicine, Sapienza University, 00161, Rome, Italy. enrico.desmaele@uniroma1.it.
Source: Oncogenesis [Oncogenesis] 2019 Nov 04; Vol. 8 (11), pp. 64. Date of Electronic Publication: 2019 Nov 04.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101580004 Publication Model: Electronic Cited Medium: Print ISSN: 2157-9024 (Print) Linking ISSN: 21579024 NLM ISO Abbreviation: Oncogenesis Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2.
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  Data: <searchLink fieldCode="AU" term="%22Spiombi+E%22">Spiombi E</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy.; Department of Medical Biotechnology and Translational Medicine, University of Milan, 20090, Segrate, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Angrisani+A%22">Angrisani A</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Fonte+S%22">Fonte S</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22De+Feudis+G%22">De Feudis G</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy.; Department of Experimental Oncology, European Institute of Oncology, 20139, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Fabretti+F%22">Fabretti F</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Cucchi+D%22">Cucchi D</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy.; Barts Cancer Institute, Queen Mary University of London, Centre for Molecular Oncology, John Vane Science Center, London, EC1M 6BQ, UK.<br /><searchLink fieldCode="AU" term="%22Izzo+M%22">Izzo M</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy.; Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Infante+P%22">Infante P</searchLink>; Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Miele+E%22">Miele E</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy.; Department of Hematology/Oncology and Stem Cell Transplantation, Bambino Gesù Children's Hospital, IRCCS, 00165, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Po+A%22">Po A</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Magno+L%22">Di Magno L</searchLink>; Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Magliozzi+R%22">Magliozzi R</searchLink>; Kymab ltd, Babraham Campus, Cambridge, CB22 3AT, UK.<br /><searchLink fieldCode="AU" term="%22Guardavaccaro+D%22">Guardavaccaro D</searchLink>; Department of Biotechnology, University of Verona, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Maroder+M%22">Maroder M</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Canettieri+G%22">Canettieri G</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy.; Istituto Pasteur, Fondazione Cenci-Bolognetti, Sapienza University of Rome, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Giannini+G%22">Giannini G</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy.; Istituto Pasteur, Fondazione Cenci-Bolognetti, Sapienza University of Rome, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Ferretti+E%22">Ferretti E</searchLink>; Department of Experimental Medicine, Sapienza University, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Gulino+A%22">Gulino A</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Marcotullio+L%22">Di Marcotullio L</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, 00161, Rome, Italy.; Istituto Pasteur, Fondazione Cenci-Bolognetti, Sapienza University of Rome, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Moretti+M%22">Moretti M</searchLink>; Department of Experimental Medicine, Sapienza University, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22De+Smaele+E%22">De Smaele E</searchLink>; Department of Experimental Medicine, Sapienza University, 00161, Rome, Italy. enrico.desmaele@uniroma1.it.
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  Data: <searchLink fieldCode="JN" term="%22101580004%22">Oncogenesis</searchLink> [Oncogenesis] 2019 Nov 04; Vol. 8 (11), pp. 64. <i>Date of Electronic Publication: </i>2019 Nov 04.
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