A novel in situ multiplex immunofluorescence panel for the assessment of tumor immunopathology and response to virotherapy in pediatric glioblastoma reveals a role for checkpoint protein inhibition.
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| Title: | A novel in situ multiplex immunofluorescence panel for the assessment of tumor immunopathology and response to virotherapy in pediatric glioblastoma reveals a role for checkpoint protein inhibition. |
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| Authors: | Bernstock JD; Medical Scientist Training Program, University of Alabama at Birmingham, Birmingham, AL, USA.; Department of Neurosurgery, Brigham and Women's, Harvard Medical School, Boston, MA, USA., Vicario N; Department of Biomedical and Biotechnological Sciences, Physiology Section, University of Catania, Catania, Italy., Rong L; Department of Pathology, Children's of Alabama, University of Alabama at Birmingham, Birmingham, AL, USA., Valdes PA; Department of Neurosurgery, Brigham and Women's, Harvard Medical School, Boston, MA, USA., Choi BD; Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Chen JA; Medical Scientist Training Program, David Geffen School of Medicine, University of California, Los Angeles, CA, USA., DiToro D; Medical Scientist Training Program, University of Alabama at Birmingham, Birmingham, AL, USA.; Department of Pathology, Brigham and Women's, Harvard Medical School, Boston, MA, USA., Osorio DS; Division of Pediatric Hematology/Oncology, Nationwide Children's Hospital, The Ohio State University, Columbus, OH, USA., Kachurak K; Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA., Gessler F; Department for Neurosurgery, Goethe University Frankfurt, Frankfurt am Main, Germany., Johnston JM Jr; Department of Neurosurgery, University of Alabama at Birmingham, Birmingham, AL, USA., Atkinson TP; Division of Pediatric Allergy, Asthma & Immunology, Department of Pediatrics and Diagnostic Mycoplasma Laboratory, Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA., Whitley RJ; Division of Infectious Diseases, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA., Bag AK; Division of Neuroradiology, Department of Radiology, University of Alabama at Birmingham, Birmingham, AL, USA., Gillespie GY; Department of Neurosurgery, University of Alabama at Birmingham, Birmingham, AL, USA., Markert JM; Department of Neurosurgery, University of Alabama at Birmingham, Birmingham, AL, USA., Maric D; Flow and Imaging Cytometry Core Facility, National Institute of Neurological Disordersand Stroke, National Institutes of Health (NINDS/NIH), Bethesda, MD, USA., Friedman GK; Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA.; Department of Neurosurgery, University of Alabama at Birmingham, Birmingham, AL, USA. |
| Source: | Oncoimmunology [Oncoimmunology] 2019 Oct 21; Vol. 8 (12), pp. e1678921. Date of Electronic Publication: 2019 Oct 21 (Print Publication: 2019). |
| Publication Type: | Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101570526 Publication Model: eCollection Cited Medium: Print ISSN: 2162-4011 (Print) Linking ISSN: 21624011 NLM ISO Abbreviation: Oncoimmunology Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2162-4011 |
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| DOI: | 10.1080/2162402X.2019.1678921 |
