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Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity.

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Bibliographic Details
Title: Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity.
Authors: Angiari S; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, 152-160 Pearse Street, Dublin D02 R590, Ireland. Electronic address: angiaris@tcd.ie., Runtsch MC; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, 152-160 Pearse Street, Dublin D02 R590, Ireland., Sutton CE; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, 152-160 Pearse Street, Dublin D02 R590, Ireland., Palsson-McDermott EM; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, 152-160 Pearse Street, Dublin D02 R590, Ireland., Kelly B; Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany., Rana N; Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany., Kane H; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, 152-160 Pearse Street, Dublin D02 R590, Ireland., Papadopoulou G; Cellular Immunology Laboratory, Center for Basic Research, Biomedical Research Foundation of the Academy of Athens 115 27, Athens, Greece., Pearce EL; Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany., Mills KHG; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, 152-160 Pearse Street, Dublin D02 R590, Ireland., O'Neill LAJ; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, 152-160 Pearse Street, Dublin D02 R590, Ireland. Electronic address: laoneill@tcd.ie.
Source: Cell metabolism [Cell Metab] 2020 Feb 04; Vol. 31 (2), pp. 391-405.e8. Date of Electronic Publication: 2019 Nov 21.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101233170 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-7420 (Electronic) Linking ISSN: 15504131 NLM ISO Abbreviation: Cell Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1932-7420
DOI:10.1016/j.cmet.2019.10.015