EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex.
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| Title: | EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex. |
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| Authors: | Hsu JH; Oncology R&D, AstraZeneca, Waltham, MA 02451, USA., Rasmusson T; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Waltham, MA 02451, USA., Robinson J; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge CB4 0FZ, UK., Pachl F; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Waltham, MA 02451, USA., Read J; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge CB4 0FZ, UK., Kawatkar S; Oncology R&D, AstraZeneca, Waltham, MA 02451, USA., O' Donovan DH; Oncology R&D, AstraZeneca, Cambridge CB4 0FZ, UK., Bagal S; Oncology R&D, AstraZeneca, Cambridge CB4 0FZ, UK., Code E; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Waltham, MA 02451, USA., Rawlins P; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge CB4 0FZ, UK., Argyrou A; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge CB4 0FZ, UK., Tomlinson R; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Waltham, MA 02451, USA., Gao N; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Waltham, MA 02451, USA., Zhu X; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Waltham, MA 02451, USA., Chiarparin E; Oncology R&D, AstraZeneca, Cambridge CB4 0FZ, UK., Jacques K; Oncology R&D, AstraZeneca, Waltham, MA 02451, USA., Shen M; Oncology R&D, AstraZeneca, Waltham, MA 02451, USA., Woods H; Oncology R&D, AstraZeneca, Waltham, MA 02451, USA., Bednarski E; Oncology R&D, AstraZeneca, Waltham, MA 02451, USA., Wilson DM; Oncology R&D, AstraZeneca, Cambridge CB4 0FZ, UK., Drew L; Oncology R&D, AstraZeneca, Waltham, MA 02451, USA., Castaldi MP; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Waltham, MA 02451, USA., Fawell S; Oncology R&D, AstraZeneca, Waltham, MA 02451, USA., Bloecher A; Oncology R&D, AstraZeneca, Waltham, MA 02451, USA. Electronic address: andrew.bloecher@astrazeneca.com. |
| Source: | Cell chemical biology [Cell Chem Biol] 2020 Jan 16; Vol. 27 (1), pp. 41-46.e17. Date of Electronic Publication: 2019 Nov 27. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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