USP22-dependent HSP90AB1 expression promotes resistance to HSP90 inhibition in mammary and colorectal cancer.

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Title: USP22-dependent HSP90AB1 expression promotes resistance to HSP90 inhibition in mammary and colorectal cancer.
Authors: Kosinsky RL; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Justus-von-Liebig-Weg 11, 37077, Göttingen, Germany. robyn-laura.kosinsky@zentr.uni-goettingen.de., Helms M; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Justus-von-Liebig-Weg 11, 37077, Göttingen, Germany., Zerche M; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Justus-von-Liebig-Weg 11, 37077, Göttingen, Germany., Wohn L; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Justus-von-Liebig-Weg 11, 37077, Göttingen, Germany., Dyas A; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Justus-von-Liebig-Weg 11, 37077, Göttingen, Germany., Prokakis E; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Justus-von-Liebig-Weg 11, 37077, Göttingen, Germany., Kazerouni ZB; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Justus-von-Liebig-Weg 11, 37077, Göttingen, Germany., Bedi U; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Justus-von-Liebig-Weg 11, 37077, Göttingen, Germany., Wegwitz F; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Justus-von-Liebig-Weg 11, 37077, Göttingen, Germany., Johnsen SA; Gene Regulatory Mechanisms and Molecular Epigenetics Lab, Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First St SW, Rochester, MN, USA. johnsen.steven@mayo.edu.
Source: Cell death & disease [Cell Death Dis] 2019 Dec 04; Vol. 10 (12), pp. 911. Date of Electronic Publication: 2019 Dec 04.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-4889
DOI:10.1038/s41419-019-2141-9