In vitro activity of a G-quadruplex-stabilizing small molecule that synergizes with Navitoclax to induce cytotoxicity in acute myeloid leukemia cells.
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| Title: | In vitro activity of a G-quadruplex-stabilizing small molecule that synergizes with Navitoclax to induce cytotoxicity in acute myeloid leukemia cells. |
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| Authors: | Montoya JJ; The Institute of Molecular Medicine at Phoenix Children's Hospital, 475 N 5th Street, Phoenix, AZ, 85004, USA. justinjmontoya@email.arizona.edu.; Department of Child Health, The University of Arizona College of Medicine-Phoenix, 475 N 5th Street, Phoenix, AZ, 85004, USA. justinjmontoya@email.arizona.edu., Turnidge MA; The Institute of Molecular Medicine at Phoenix Children's Hospital, 475 N 5th Street, Phoenix, AZ, 85004, USA.; Department of Child Health, The University of Arizona College of Medicine-Phoenix, 475 N 5th Street, Phoenix, AZ, 85004, USA.; School of Life Sciences, Arizona State University, Tempe, AZ, USA.; Present Address: Department of Molecular & Medical Genetics, Oregon Health and Science University, Portland, OR, 97239, USA., Wai DH; The Institute of Molecular Medicine at Phoenix Children's Hospital, 475 N 5th Street, Phoenix, AZ, 85004, USA.; Department of Child Health, The University of Arizona College of Medicine-Phoenix, 475 N 5th Street, Phoenix, AZ, 85004, USA., Patel AR; The Institute of Molecular Medicine at Phoenix Children's Hospital, 475 N 5th Street, Phoenix, AZ, 85004, USA.; Department of Child Health, The University of Arizona College of Medicine-Phoenix, 475 N 5th Street, Phoenix, AZ, 85004, USA.; Center for Cancer and Blood Disorders, Phoenix Children's Hospital, Phoenix, AZ, USA., Lee DW; The Institute of Molecular Medicine at Phoenix Children's Hospital, 475 N 5th Street, Phoenix, AZ, 85004, USA.; Department of Child Health, The University of Arizona College of Medicine-Phoenix, 475 N 5th Street, Phoenix, AZ, 85004, USA., Gokhale V; University of Arizona College of Pharmacy, Tucson, AZ, USA., Hurley LH; University of Arizona College of Pharmacy, Tucson, AZ, USA., Arceci RJ; The Institute of Molecular Medicine at Phoenix Children's Hospital, 475 N 5th Street, Phoenix, AZ, 85004, USA.; Department of Child Health, The University of Arizona College of Medicine-Phoenix, 475 N 5th Street, Phoenix, AZ, 85004, USA.; Center for Cancer and Blood Disorders, Phoenix Children's Hospital, Phoenix, AZ, USA., Wetmore C; The Institute of Molecular Medicine at Phoenix Children's Hospital, 475 N 5th Street, Phoenix, AZ, 85004, USA.; Department of Child Health, The University of Arizona College of Medicine-Phoenix, 475 N 5th Street, Phoenix, AZ, 85004, USA.; Center for Cancer and Blood Disorders, Phoenix Children's Hospital, Phoenix, AZ, USA., Azorsa DO; The Institute of Molecular Medicine at Phoenix Children's Hospital, 475 N 5th Street, Phoenix, AZ, 85004, USA.; Department of Child Health, The University of Arizona College of Medicine-Phoenix, 475 N 5th Street, Phoenix, AZ, 85004, USA.; Present Address: Systems Oncology, Scottsdale, AZ, 85255, USA. |
| Source: | BMC cancer [BMC Cancer] 2019 Dec 27; Vol. 19 (1), pp. 1251. Date of Electronic Publication: 2019 Dec 27. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1471-2407 |
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| DOI: | 10.1186/s12885-019-6464-9 |
