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The synthesis of trifluoromethylated N-nitroaryl-2-amino-1,3-dichloropropane derivatives and their evaluation as potential anti-cancer agents.

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Title: The synthesis of trifluoromethylated N-nitroaryl-2-amino-1,3-dichloropropane derivatives and their evaluation as potential anti-cancer agents.
Authors: Chappel L; Department of Applied Sciences, Northumbria University, Newcastle upon Tyne NE1 8ST, UK., Wong LC; Department of Pharmaceutical Chemistry, School of Pharmacy, International Medical University Malaysia, 57000 Kuala Lumpur, Malaysia., Leong CO; Centre for Cancer and Stem Cells Research, Institute for Research, Development and Innovation, International Medical University Malaysia, 57000 Kuala Lumpur, Malaysia; Department of Life Sciences, School of Pharmacy, International Medical University Malaysia, 57000 Kuala Lumpur, Malaysia., Mai CW; Department of Pharmaceutical Chemistry, School of Pharmacy, International Medical University Malaysia, 57000 Kuala Lumpur, Malaysia; Centre for Cancer and Stem Cells Research, Institute for Research, Development and Innovation, International Medical University Malaysia, 57000 Kuala Lumpur, Malaysia., Meikle IT; Department of Applied Sciences, Northumbria University, Newcastle upon Tyne NE1 8ST, UK., Stanforth SP; Department of Applied Sciences, Northumbria University, Newcastle upon Tyne NE1 8ST, UK. Electronic address: steven.stanforth@northumbria.ac.uk., Truong TV; Department of Applied Sciences, Northumbria University, Newcastle upon Tyne NE1 8ST, UK.
Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2020 Feb 15; Vol. 30 (4), pp. 126910. Date of Electronic Publication: 2019 Dec 19.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1464-3405
DOI:10.1016/j.bmcl.2019.126910