Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis.

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Title: Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis.
Authors: Herster F; Department of Immunology, University of Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany., Bittner Z; Department of Immunology, University of Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany., Archer NK; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD, 21231, USA., Dickhöfer S; Department of Immunology, University of Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany., Eisel D; Department of Immunology, University of Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany.; David Eisel, BioNTech, An der Goldgrube 12, 55131, Mainz, Germany., Eigenbrod T; Department of Infectious Diseases, Medical Microbiology and Hygiene, University Hospital Heidelberg, Im Neuenheimer Feld 324, 69120, Heidelberg, Germany., Knorpp T; NMI Natural and Medical Sciences Institute at the University of Tübingen, Markwiesenstr. 55, 72770, Reutlingen, Germany., Schneiderhan-Marra N; NMI Natural and Medical Sciences Institute at the University of Tübingen, Markwiesenstr. 55, 72770, Reutlingen, Germany., Löffler MW; Department of Immunology, University of Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany.; Department of General, Visceral and Transplant Surgery, University Hospital Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany.; Department of Clinical Pharmacology, University Hospital Tübingen, Auf der Morgenstelle 8, 72076, Tübingen, Germany., Kalbacher H; Interfaculty Institute of Biochemistry, University of Tübingen, Hoppe-Seyler-Str. 4, 72076, Tübingen, Germany., Vierbuchen T; Research Group Innate Immunity, Research Center Borstel, Leibniz Lung Center, Airway Research Center North (ARCN), Deutsches Zentrum für Lungenforschung (DZL), Parkallee 22, 23845, Borstel, Germany., Heine H; Research Group Innate Immunity, Research Center Borstel, Leibniz Lung Center, Airway Research Center North (ARCN), Deutsches Zentrum für Lungenforschung (DZL), Parkallee 22, 23845, Borstel, Germany., Miller LS; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD, 21231, USA., Hartl D; University Children's Hospital and Interdisciplinary Center for Infectious Diseases, University of Tübingen, Hoppe-Seyler-Str. 1, 72076, Tübingen, Germany.; Novartis Institutes for BioMedical Research (NIBR), Basel, Switzerland., Freund L; Department of Dermatology, University Hospital Heidelberg, Im Neuenheimer Feld 440, 69120, Heidelberg, Germany., Schäkel K; Department of Dermatology, University Hospital Heidelberg, Im Neuenheimer Feld 440, 69120, Heidelberg, Germany., Heister M; Department of Dermatology, University Hospital Tübingen, Liebermeisterstr. 25, 72076, Tübingen, Germany., Ghoreschi K; Department of Dermatology, University Hospital Tübingen, Liebermeisterstr. 25, 72076, Tübingen, Germany.; Department of Dermatology, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany., Weber ANR; Department of Immunology, University of Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany. alexander.weber@uni-tuebingen.de.
Source: Nature communications [Nat Commun] 2020 Jan 08; Vol. 11 (1), pp. 105. Date of Electronic Publication: 2020 Jan 08.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-019-13756-4