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The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction.

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Title: The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction.
Authors: Inda MC; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.; Hostos Community College, City University of New York, The Bronx, NY, 10451, USA., Joshi S; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Wang T; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Bolaender A; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Gandu S; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Koren Iii J; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Che AY; Brain and Mind Research Institute, Weill Cornell Medical College, New York, NY, 10065, USA., Taldone T; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Yan P; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Sun W; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Uddin M; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Panchal P; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Riolo M; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Shah S; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Barlas A; Molecular Cytology Core Facility, Memorial Sloan-Kettering Cancer Center, New York, NY, 10065, USA., Xu K; Molecular Cytology Core Facility, Memorial Sloan-Kettering Cancer Center, New York, NY, 10065, USA., Chan LYL; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Gruzinova A; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Kishinevsky S; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.; Department of Developmental Biology, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Studer L; Department of Developmental Biology, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Fossati V; The New York Stem Cell Foundation Research Institute, New York, NY, 10019, USA., Noggle SA; The New York Stem Cell Foundation Research Institute, New York, NY, 10019, USA., White JR; Comparative Pathology Laboratory, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., de Stanchina E; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Sequeira S; Office of Clinical Research, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Anthoney KH; Department of Biological Sciences, Humboldt State University, Arcata, CA, 95521, USA., Steele JW; Department of Biological Sciences, Humboldt State University, Arcata, CA, 95521, USA., Manova-Todorova K; Molecular Cytology Core Facility, Memorial Sloan-Kettering Cancer Center, New York, NY, 10065, USA., Patil S; Department of Epidemiology-Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Dunphy MP; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Pillarsetty N; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Pereira AC; Department of Neuroscience, Rockefeller University, New York, NY, 10065, USA.; Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Erdjument-Bromage H; Department of Cell Biology, NYU School of Medicine, New York, NY, 10016, USA.; Kimmel Center for Biology and Medicine at the Skirball Institute, NYU School of Medicine, New York, NY, 10016, USA., Neubert TA; Department of Cell Biology, NYU School of Medicine, New York, NY, 10016, USA.; Kimmel Center for Biology and Medicine at the Skirball Institute, NYU School of Medicine, New York, NY, 10016, USA., Rodina A; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Ginsberg SD; Departments of Psychiatry, Neuroscience & Physiology & the NYU Neuroscience Institute, NYU School of Medicine, New York, NY, 10016, USA.; Center for Dementia Research, Nathan Kline Institute, Orangeburg, NY, 10962, USA., De Marco Garcia N; Brain and Mind Research Institute, Weill Cornell Medical College, New York, NY, 10065, USA., Luo W; Brain and Mind Research Institute, Weill Cornell Medical College, New York, NY, 10065, USA. wel2009@med.cornell.edu., Chiosis G; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA. chiosisg@mskcc.org.
Source: Nature communications [Nat Commun] 2020 Jan 16; Vol. 11 (1), pp. 319. Date of Electronic Publication: 2020 Jan 16.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-019-14082-5