Overexpression of transcription factor Foxa1 and target genes remediate therapeutic protein production bottlenecks in Chinese hamster ovary cells.
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| Title: | Overexpression of transcription factor Foxa1 and target genes remediate therapeutic protein production bottlenecks in Chinese hamster ovary cells. |
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| Authors: | Berger A; Department of Fundamental Microbiology, Institute of Biotechnology, University of Lausanne, Lausanne, Switzerland.; Present address: Laboratory of Microsystems LMIS4, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Le Fourn V; Selexis SA, Geneva, Switzerland., Masternak J; Department of Fundamental Microbiology, Institute of Biotechnology, University of Lausanne, Lausanne, Switzerland., Regamey A; Selexis SA, Geneva, Switzerland., Bodenmann I; Selexis SA, Geneva, Switzerland., Girod PA; Selexis SA, Geneva, Switzerland., Mermod N; Department of Fundamental Microbiology, Institute of Biotechnology, University of Lausanne, Lausanne, Switzerland. |
| Source: | Biotechnology and bioengineering [Biotechnol Bioeng] 2020 Apr; Vol. 117 (4), pp. 1101-1116. Date of Electronic Publication: 2020 Feb 23. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 7502021 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0290 (Electronic) Linking ISSN: 00063592 NLM ISO Abbreviation: Biotechnol Bioeng Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1097-0290 |
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| DOI: | 10.1002/bit.27274 |
