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Phase I trial of donor-derived modified immune cell infusion in kidney transplantation.

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Title: Phase I trial of donor-derived modified immune cell infusion in kidney transplantation.
Authors: Morath C; Department of Nephrology, Heidelberg University Hospital, Heidelberg, Germany.; TolerogenixX GmbH, Heidelberg, Germany., Schmitt A; TolerogenixX GmbH, Heidelberg, Germany.; Department of Hematology, Oncology and Rheumatology., Kleist C; Transplantation Immunology, Institute of Immunology.; Department of Nuclear Medicine., Daniel V; Transplantation Immunology, Institute of Immunology., Opelz G; Transplantation Immunology, Institute of Immunology., Süsal C; Transplantation Immunology, Institute of Immunology., Ibrahim E; Transplantation Immunology, Institute of Immunology., Kälble F; Department of Nephrology, Heidelberg University Hospital, Heidelberg, Germany., Speer C; Department of Nephrology, Heidelberg University Hospital, Heidelberg, Germany., Nusshag C; Department of Nephrology, Heidelberg University Hospital, Heidelberg, Germany., Pego da Silva L; Department of Nephrology, Heidelberg University Hospital, Heidelberg, Germany.; TolerogenixX GmbH, Heidelberg, Germany., Sommerer C; Department of Nephrology, Heidelberg University Hospital, Heidelberg, Germany., Wang L; TolerogenixX GmbH, Heidelberg, Germany.; Department of Hematology, Oncology and Rheumatology., Ni M; Department of Hematology, Oncology and Rheumatology., Hückelhoven-Krauss A; Department of Hematology, Oncology and Rheumatology., Czock D; Department of Clinical Pharmacology and Pharmacoepidemiology., Merle U; Department of Gastroenterology., Mehrabi A; Department of General, Visceral and Transplantation Surgery., Sander A; Institute of Medical Biometry and Informatics., Hackbusch M; Institute of Medical Biometry and Informatics., Eckert C; Institute of Pathology, and., Waldherr R; Institute of Pathology, and., Schnitzler P; Virology, Center for Infectious Diseases, Heidelberg University Hospital, Heidelberg, Germany., Müller-Tidow C; Department of Hematology, Oncology and Rheumatology., Hoheisel JD; Division of Functional Genome Analysis, DKFZ, Heidelberg, Germany., Mustafa SA; Division of Functional Genome Analysis, DKFZ, Heidelberg, Germany.; Kurdistan Institution for Strategic Studies and Scientific Research, Kurdistan Region, Iraq., Alhamdani MS; Division of Functional Genome Analysis, DKFZ, Heidelberg, Germany., Bauer AS; Division of Functional Genome Analysis, DKFZ, Heidelberg, Germany., Reiser J; Department of Medicine, Rush Medical College, Rush University, Chicago, Illinois, USA., Zeier M; Department of Nephrology, Heidelberg University Hospital, Heidelberg, Germany., Schmitt M; Department of Hematology, Oncology and Rheumatology., Schaier M; Department of Nephrology, Heidelberg University Hospital, Heidelberg, Germany.; TolerogenixX GmbH, Heidelberg, Germany., Terness P; Transplantation Immunology, Institute of Immunology.
Source: The Journal of clinical investigation [J Clin Invest] 2020 May 01; Vol. 130 (5), pp. 2364-2376.
Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Morath+C%22">Morath C</searchLink>; Department of Nephrology, Heidelberg University Hospital, Heidelberg, Germany.; TolerogenixX GmbH, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Schmitt+A%22">Schmitt A</searchLink>; TolerogenixX GmbH, Heidelberg, Germany.; Department of Hematology, Oncology and Rheumatology.<br /><searchLink fieldCode="AU" term="%22Kleist+C%22">Kleist C</searchLink>; Transplantation Immunology, Institute of Immunology.; Department of Nuclear Medicine.<br /><searchLink fieldCode="AU" term="%22Daniel+V%22">Daniel V</searchLink>; Transplantation Immunology, Institute of Immunology.<br /><searchLink fieldCode="AU" term="%22Opelz+G%22">Opelz G</searchLink>; Transplantation Immunology, Institute of Immunology.<br /><searchLink fieldCode="AU" term="%22Süsal+C%22">Süsal C</searchLink>; Transplantation Immunology, Institute of Immunology.<br /><searchLink fieldCode="AU" term="%22Ibrahim+E%22">Ibrahim E</searchLink>; Transplantation Immunology, Institute of Immunology.<br /><searchLink fieldCode="AU" term="%22Kälble+F%22">Kälble F</searchLink>; Department of Nephrology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Speer+C%22">Speer C</searchLink>; Department of Nephrology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Nusshag+C%22">Nusshag C</searchLink>; Department of Nephrology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Pego+da+Silva+L%22">Pego da Silva L</searchLink>; Department of Nephrology, Heidelberg University Hospital, Heidelberg, Germany.; TolerogenixX GmbH, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Sommerer+C%22">Sommerer C</searchLink>; Department of Nephrology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; TolerogenixX GmbH, Heidelberg, Germany.; Department of Hematology, Oncology and Rheumatology.<br /><searchLink fieldCode="AU" term="%22Ni+M%22">Ni M</searchLink>; Department of Hematology, Oncology and Rheumatology.<br /><searchLink fieldCode="AU" term="%22Hückelhoven-Krauss+A%22">Hückelhoven-Krauss A</searchLink>; Department of Hematology, Oncology and Rheumatology.<br /><searchLink fieldCode="AU" term="%22Czock+D%22">Czock D</searchLink>; Department of Clinical Pharmacology and Pharmacoepidemiology.<br /><searchLink fieldCode="AU" term="%22Merle+U%22">Merle U</searchLink>; Department of Gastroenterology.<br /><searchLink fieldCode="AU" term="%22Mehrabi+A%22">Mehrabi A</searchLink>; Department of General, Visceral and Transplantation Surgery.<br /><searchLink fieldCode="AU" term="%22Sander+A%22">Sander A</searchLink>; Institute of Medical Biometry and Informatics.<br /><searchLink fieldCode="AU" term="%22Hackbusch+M%22">Hackbusch M</searchLink>; Institute of Medical Biometry and Informatics.<br /><searchLink fieldCode="AU" term="%22Eckert+C%22">Eckert C</searchLink>; Institute of Pathology, and.<br /><searchLink fieldCode="AU" term="%22Waldherr+R%22">Waldherr R</searchLink>; Institute of Pathology, and.<br /><searchLink fieldCode="AU" term="%22Schnitzler+P%22">Schnitzler P</searchLink>; Virology, Center for Infectious Diseases, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Müller-Tidow+C%22">Müller-Tidow C</searchLink>; Department of Hematology, Oncology and Rheumatology.<br /><searchLink fieldCode="AU" term="%22Hoheisel+JD%22">Hoheisel JD</searchLink>; Division of Functional Genome Analysis, DKFZ, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Mustafa+SA%22">Mustafa SA</searchLink>; Division of Functional Genome Analysis, DKFZ, Heidelberg, Germany.; Kurdistan Institution for Strategic Studies and Scientific Research, Kurdistan Region, Iraq.<br /><searchLink fieldCode="AU" term="%22Alhamdani+MS%22">Alhamdani MS</searchLink>; Division of Functional Genome Analysis, DKFZ, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Bauer+AS%22">Bauer AS</searchLink>; Division of Functional Genome Analysis, DKFZ, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Reiser+J%22">Reiser J</searchLink>; Department of Medicine, Rush Medical College, Rush University, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Zeier+M%22">Zeier M</searchLink>; Department of Nephrology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Schmitt+M%22">Schmitt M</searchLink>; Department of Hematology, Oncology and Rheumatology.<br /><searchLink fieldCode="AU" term="%22Schaier+M%22">Schaier M</searchLink>; Department of Nephrology, Heidelberg University Hospital, Heidelberg, Germany.; TolerogenixX GmbH, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Terness+P%22">Terness P</searchLink>; Transplantation Immunology, Institute of Immunology.
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