AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.

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Title: AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.
Authors: Jia J; Autophagy, Inflammation and Metabolism AIM Center of Biochemical Research Excellence, University of New Mexico Health Sciences Center, Albuquerque, NM, USA; Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, NM, USA., Bissa B; Autophagy, Inflammation and Metabolism AIM Center of Biochemical Research Excellence, University of New Mexico Health Sciences Center, Albuquerque, NM, USA; Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, NM, USA., Brecht L; Munich Cluster of Systems Neurology, Munich, Germany., Allers L; Autophagy, Inflammation and Metabolism AIM Center of Biochemical Research Excellence, University of New Mexico Health Sciences Center, Albuquerque, NM, USA; Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, NM, USA., Choi SW; Autophagy, Inflammation and Metabolism AIM Center of Biochemical Research Excellence, University of New Mexico Health Sciences Center, Albuquerque, NM, USA; Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, NM, USA., Gu Y; Autophagy, Inflammation and Metabolism AIM Center of Biochemical Research Excellence, University of New Mexico Health Sciences Center, Albuquerque, NM, USA; Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, NM, USA., Zbinden M; Human Metabolome Technologies America, Boston, MA, USA., Burge MR; Autophagy, Inflammation and Metabolism AIM Center of Biochemical Research Excellence, University of New Mexico Health Sciences Center, Albuquerque, NM, USA; Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM, USA., Timmins G; Autophagy, Inflammation and Metabolism AIM Center of Biochemical Research Excellence, University of New Mexico Health Sciences Center, Albuquerque, NM, USA; School pf Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, NM, USA., Hallows K; Division of Nephrology and Hypertension, Department of Medicine and USC/UKRO Kidney Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Behrends C; Munich Cluster of Systems Neurology, Munich, Germany., Deretic V; Autophagy, Inflammation and Metabolism AIM Center of Biochemical Research Excellence, University of New Mexico Health Sciences Center, Albuquerque, NM, USA; Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, NM, USA. Electronic address: vderetic@salud.unm.edu.
Source: Molecular cell [Mol Cell] 2020 Mar 05; Vol. 77 (5), pp. 951-969.e9. Date of Electronic Publication: 2020 Jan 28.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1097-4164
DOI:10.1016/j.molcel.2019.12.028