Structural basis of second-generation HIV integrase inhibitor action and viral resistance.
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| Title: | Structural basis of second-generation HIV integrase inhibitor action and viral resistance. |
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| Authors: | Cook NJ; Chromatin Structure and Mobile DNA Laboratory, Francis Crick Institute, London NW1 1AT, UK., Li W; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA., Berta D; Department of Chemistry, King's College London, London SE1 1DB, UK., Badaoui M; Department of Chemistry, King's College London, London SE1 1DB, UK., Ballandras-Colas A; Chromatin Structure and Mobile DNA Laboratory, Francis Crick Institute, London NW1 1AT, UK., Nans A; Structural Biology Science Technology Platform, Francis Crick Institute, London NW1 1AT, UK., Kotecha A; The Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Materials and Structural Analysis, Thermo Fisher Scientific, Eindhoven, 5651 GG, Netherlands., Rosta E; Department of Chemistry, King's College London, London SE1 1DB, UK., Engelman AN; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215, USA. peter.cherepanov@crick.ac.uk alan_engelman@dfci.harvard.edu.; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA., Cherepanov P; Chromatin Structure and Mobile DNA Laboratory, Francis Crick Institute, London NW1 1AT, UK. peter.cherepanov@crick.ac.uk alan_engelman@dfci.harvard.edu.; Department of Infectious Disease, Imperial College London, St Mary's Campus, London W2 1PG, UK. |
| Source: | Science (New York, N.Y.) [Science] 2020 Feb 14; Vol. 367 (6479), pp. 806-810. Date of Electronic Publication: 2020 Jan 30. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1095-9203 |
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| DOI: | 10.1126/science.aay4919 |
