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Convergence of pathway analysis and pattern recognition predicts sensitization to latest generation TRAIL therapeutics by IAP antagonism.

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Title: Convergence of pathway analysis and pattern recognition predicts sensitization to latest generation TRAIL therapeutics by IAP antagonism.
Authors: Vetma V; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany.; Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland., Guttà C; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany., Peters N; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany., Praetorius C; Center for Regenerative Therapies, Technical University Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Centre, Department of Dermatology, Faculty of Medicine, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany., Hutt M; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany., Seifert O; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany., Meier F; Skin Cancer Center at the University Cancer Centre, Department of Dermatology, Faculty of Medicine, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.; National Center for Tumor Diseases (NCT), Dresden, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany., Kontermann R; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany.; Stuttgart Research Center Systems Biology, University of Stuttgart, Stuttgart, Germany., Kulms D; Center for Regenerative Therapies, Technical University Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Centre, Department of Dermatology, Faculty of Medicine, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.; Experimental Dermatology, Department of Dermatology, Technical University Dresden, Dresden, Germany., Rehm M; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany. markus.morrison@izi.uni-stuttgart.de.; Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland. markus.morrison@izi.uni-stuttgart.de.; Stuttgart Research Center Systems Biology, University of Stuttgart, Stuttgart, Germany. markus.morrison@izi.uni-stuttgart.de.; Stuttgart Centre for Simulation Science (SC SimTech), University of Stuttgart, Stuttgart, Germany. markus.morrison@izi.uni-stuttgart.de.; Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland. markus.morrison@izi.uni-stuttgart.de.
Source: Cell death and differentiation [Cell Death Differ] 2020 Aug; Vol. 27 (8), pp. 2417-2432. Date of Electronic Publication: 2020 Feb 21.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9437445 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5403 (Electronic) Linking ISSN: 13509047 NLM ISO Abbreviation: Cell Death Differ Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Convergence of pathway analysis and pattern recognition predicts sensitization to latest generation TRAIL therapeutics by IAP antagonism.
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  Data: <searchLink fieldCode="AU" term="%22Vetma+V%22">Vetma V</searchLink>; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany.; Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Guttà+C%22">Guttà C</searchLink>; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany.<br /><searchLink fieldCode="AU" term="%22Peters+N%22">Peters N</searchLink>; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany.<br /><searchLink fieldCode="AU" term="%22Praetorius+C%22">Praetorius C</searchLink>; Center for Regenerative Therapies, Technical University Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Centre, Department of Dermatology, Faculty of Medicine, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Hutt+M%22">Hutt M</searchLink>; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany.<br /><searchLink fieldCode="AU" term="%22Seifert+O%22">Seifert O</searchLink>; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany.<br /><searchLink fieldCode="AU" term="%22Meier+F%22">Meier F</searchLink>; Skin Cancer Center at the University Cancer Centre, Department of Dermatology, Faculty of Medicine, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.; National Center for Tumor Diseases (NCT), Dresden, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Kontermann+R%22">Kontermann R</searchLink>; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany.; Stuttgart Research Center Systems Biology, University of Stuttgart, Stuttgart, Germany.<br /><searchLink fieldCode="AU" term="%22Kulms+D%22">Kulms D</searchLink>; Center for Regenerative Therapies, Technical University Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Centre, Department of Dermatology, Faculty of Medicine, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.; Experimental Dermatology, Department of Dermatology, Technical University Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Rehm+M%22">Rehm M</searchLink>; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany. markus.morrison@izi.uni-stuttgart.de.; Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland. markus.morrison@izi.uni-stuttgart.de.; Stuttgart Research Center Systems Biology, University of Stuttgart, Stuttgart, Germany. markus.morrison@izi.uni-stuttgart.de.; Stuttgart Centre for Simulation Science (SC SimTech), University of Stuttgart, Stuttgart, Germany. markus.morrison@izi.uni-stuttgart.de.; Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland. markus.morrison@izi.uni-stuttgart.de.
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              Text: 2020 Aug
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