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Leveraging Human Genetics to Identify Safety Signals Prior to Drug Marketing Approval and Clinical Use.

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Title: Leveraging Human Genetics to Identify Safety Signals Prior to Drug Marketing Approval and Clinical Use.
Authors: Jerome RN; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA. rebecca.jerome@vumc.org., Joly MM; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA., Kennedy N; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA., Shirey-Rice JK; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA., Roden DM; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA., Bernard GR; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA., Holroyd KJ; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.; Center for Technology Transfer and Commercialization, Vanderbilt University, Nashville, TN, USA., Denny JC; Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA., Pulley JM; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.
Source: Drug safety [Drug Saf] 2020 Jun; Vol. 43 (6), pp. 567-582.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 9002928 Publication Model: Print Cited Medium: Internet ISSN: 1179-1942 (Electronic) Linking ISSN: 01145916 NLM ISO Abbreviation: Drug Saf Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Jerome+RN%22">Jerome RN</searchLink>; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA. rebecca.jerome@vumc.org.<br /><searchLink fieldCode="AU" term="%22Joly+MM%22">Joly MM</searchLink>; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Kennedy+N%22">Kennedy N</searchLink>; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Shirey-Rice+JK%22">Shirey-Rice JK</searchLink>; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Roden+DM%22">Roden DM</searchLink>; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Bernard+GR%22">Bernard GR</searchLink>; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Holroyd+KJ%22">Holroyd KJ</searchLink>; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.; Center for Technology Transfer and Commercialization, Vanderbilt University, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Denny+JC%22">Denny JC</searchLink>; Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Pulley+JM%22">Pulley JM</searchLink>; Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Adis%2C+Springer+International%22">Adis, Springer International </searchLink><i>Country of Publication: </i>New Zealand <i>NLM ID: </i>9002928 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1179-1942 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201145916%22">01145916 </searchLink><i>NLM ISO Abbreviation: </i>Drug Saf <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s40264-020-00915-6
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        Text: English
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              M: 06
              Text: 2020 Jun
              Type: published
              Y: 2020
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