A positron emission tomography imaging study to confirm target engagement in the lungs of patients with idiopathic pulmonary fibrosis following a single dose of a novel inhaled αvβ6 integrin inhibitor.
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| Title: | A positron emission tomography imaging study to confirm target engagement in the lungs of patients with idiopathic pulmonary fibrosis following a single dose of a novel inhaled αvβ6 integrin inhibitor. |
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| Authors: | Maher TM; Royal Brompton Hospital, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK., Simpson JK; GlaxoSmithKline Research and Development, Stevenage, UK., Porter JC; University College London Hospital, London, UK., Wilson FJ; GlaxoSmithKline Research and Development, Stevenage, UK., Chan R; GlaxoSmithKline Research and Development, Stevenage, UK., Eames R; GlaxoSmithKline Research and Development, Stevenage, UK., Cui Y; GlaxoSmithKline Research and Development, Stevenage, UK., Siederer S; GlaxoSmithKline Research and Development, Stevenage, UK., Parry S; GlaxoSmithKline Research and Development, Stevenage, UK., Kenny J; GlaxoSmithKline Research and Development, Stevenage, UK., Slack RJ; GlaxoSmithKline Research and Development, Stevenage, UK., Sahota J; University College London Hospital, London, UK., Paul L; Royal Brompton Hospital, London, UK., Saunders P; Royal Brompton Hospital, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK., Molyneaux PL; Royal Brompton Hospital, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK., Lukey PT; GlaxoSmithKline Research and Development, Stevenage, UK., Rizzo G; Invicro, A Konica Minolta Company, London, UK., Searle GE; Invicro, A Konica Minolta Company, London, UK., Marshall RP; GlaxoSmithKline Research and Development, Stevenage, UK., Saleem A; Invicro, A Konica Minolta Company, London, UK., Kang'ombe AR; GlaxoSmithKline Research and Development, Stevenage, UK., Fairman D; GlaxoSmithKline Research and Development, Stevenage, UK., Fahy WA; GlaxoSmithKline Research and Development, Stevenage, UK., Vahdati-Bolouri M; GlaxoSmithKline Research and Development, Stevenage, UK. mitra.x.vahdati-bolouri@gsk.com. |
| Source: | Respiratory research [Respir Res] 2020 Mar 26; Vol. 21 (1), pp. 75. Date of Electronic Publication: 2020 Mar 26. |
| Publication Type: | Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial |
| Journal Info: | Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101090633 Publication Model: Electronic Cited Medium: Internet ISSN: 1465-993X (Electronic) Linking ISSN: 14659921 NLM ISO Abbreviation: Respir Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1465-993X |
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| DOI: | 10.1186/s12931-020-01339-7 |
