Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia.
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| Title: | Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia. |
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| Authors: | Hysi PG; Section of Ophthalmology, School of Life Course Sciences, King's College London, London, UK. pirro.hysi@kcl.ac.uk.; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK. pirro.hysi@kcl.ac.uk.; UCL Great Ormond Street Institute of Child Health, University College London, London, UK. pirro.hysi@kcl.ac.uk., Choquet H; Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA., Khawaja AP; NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.; Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge School of Clinical Medicine, Cambridge, UK., Wojciechowski R; Department of Biophysics, Johns Hopkins University, Baltimore, MD, USA.; Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, MD, USA., Tedja MS; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Yin J; Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA., Simcoe MJ; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Patasova K; Section of Ophthalmology, School of Life Course Sciences, King's College London, London, UK., Mahroo OA; Section of Ophthalmology, School of Life Course Sciences, King's College London, London, UK.; NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK., Thai KK; Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA., Cumberland PM; UCL Great Ormond Street Institute of Child Health, University College London, London, UK.; Ulverscroft Vision Research Group, UCL Great Ormond Street Institute of Child Health, University College London, London, UK., Melles RB; Department of Ophthalmology Kaiser Permanente Northern California, Redwood City, CA, USA., Verhoeven VJM; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Clinical Genetics, Erasmus Medical Center, Rotterdam, the Netherlands., Vitart V; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK., Segre A; Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear, Boston, MA, USA., Stone RA; Department of Ophthalmology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Wareham N; Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge School of Clinical Medicine, Cambridge, UK., Hewitt AW; Department of Ophthalmology, Royal Hobart Hospital, Hobart, Tasmania, Australia., Mackey DA; Department of Ophthalmology, Royal Hobart Hospital, Hobart, Tasmania, Australia.; Centre for Ophthalmology and Visual Science, University of Western Australia, Lions Eye Institute, Perth, Western Australia, Australia., Klaver CCW; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Ophthalmology, Radboud University Medical Center, Rotterdam, the Netherlands.; Institute of Molecular and Clinical Ophthalmology Basel, Basel, Switzerland., MacGregor S; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Khaw PT; NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK., Foster PJ; NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.; Division of Genetics and Epidemiology, UCL Institute of Ophthalmology, London, UK., Guggenheim JA; School of Optometry & Vision Sciences, Cardiff University, Cardiff, UK., Rahi JS; UCL Great Ormond Street Institute of Child Health, University College London, London, UK.; NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.; Ulverscroft Vision Research Group, UCL Great Ormond Street Institute of Child Health, University College London, London, UK.; Department of Ophthalmology and NIHR, Biomedical Research Centre, Great Ormond Street Hospital NHS Foundation Trust, London, UK., Jorgenson E; Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA., Hammond CJ; Section of Ophthalmology, School of Life Course Sciences, King's College London, London, UK.; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK. |
| Corporate Authors: | Consortium for Refractive Error and Myopia, UK Eye and Vision Consortium, 23andMe Inc. |
| Source: | Nature genetics [Nat Genet] 2020 Apr; Vol. 52 (4), pp. 401-407. Date of Electronic Publication: 2020 Mar 30. |
| Publication Type: | Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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